Decreased serum brain-derived neurotrophic factor in trained men - PubMed (original) (raw)
. 2008 May 23;437(1):29-32.
doi: 10.1016/j.neulet.2008.03.057. Epub 2008 Mar 26.
Affiliations
- PMID: 18420345
- DOI: 10.1016/j.neulet.2008.03.057
Decreased serum brain-derived neurotrophic factor in trained men
Yu Nofuji et al. Neurosci Lett. 2008.
Abstract
The purpose of this study was to clarify the effect of physical activity on the level of serum brain-derived neurotrophic factor (BDNF). The serum BDNF level in trained men who have participated in regular sport activity (n=12) was compared to that in sedentary subjects (n=14). The physical activity levels expressed as total energy expenditure, move-related energy expenditure and walking count in the trained were significantly higher than those in the sedentary. The serum BDNF level in the trained men was found to be lower than that in the sedentary (19.54+/-4.53 ng/ml vs. 23.63+/-2.94 ng/ml, respectively, P<0.01). The serum BDNF level showed a significant negative correlation with daily total energy expenditure (r=-0.507, P<0.05), movement-related energy expenditure (r=-0.503, P<0.05), and walking count (r=-0.480, P<0.05). These results may suggest that vigorous habitual physical activity decrease the serum BDNF level.
Similar articles
- Cardio-respiratory fitness, habitual physical activity and serum brain derived neurotrophic factor (BDNF) in men and women.
Currie J, Ramsbottom R, Ludlow H, Nevill A, Gilder M. Currie J, et al. Neurosci Lett. 2009 Feb 20;451(2):152-5. doi: 10.1016/j.neulet.2008.12.043. Epub 2008 Dec 25. Neurosci Lett. 2009. PMID: 19133315 - Relationships between components of physical activity, cardiorespiratory fitness, cardiac autonomic health, and brain-derived neurotrophic factor.
Ramsbottom R, Currie J, Gilder M. Ramsbottom R, et al. J Sports Sci. 2010 Jun;28(8):843-9. doi: 10.1080/02640411003702686. J Sports Sci. 2010. PMID: 20480426 Clinical Trial. - Serum brain-derived neurotrophic factor level is increased and associated with obesity in newly diagnosed female patients with type 2 diabetes mellitus.
Suwa M, Kishimoto H, Nofuji Y, Nakano H, Sasaki H, Radak Z, Kumagai S. Suwa M, et al. Metabolism. 2006 Jul;55(7):852-7. doi: 10.1016/j.metabol.2006.02.012. Metabolism. 2006. PMID: 16784955 - The effects of physical activity and exercise on brain-derived neurotrophic factor in healthy humans: A review.
Huang T, Larsen KT, Ried-Larsen M, Møller NC, Andersen LB. Huang T, et al. Scand J Med Sci Sports. 2014 Feb;24(1):1-10. doi: 10.1111/sms.12069. Epub 2013 Apr 22. Scand J Med Sci Sports. 2014. PMID: 23600729 Review. - Behavioral and serotonergic consequences of decreasing or increasing hippocampus brain-derived neurotrophic factor protein levels in mice.
Deltheil T, Guiard BP, Cerdan J, David DJ, Tanaka KF, Repérant C, Guilloux JP, Coudoré F, Hen R, Gardier AM. Deltheil T, et al. Neuropharmacology. 2008 Nov;55(6):1006-14. doi: 10.1016/j.neuropharm.2008.08.001. Epub 2008 Aug 12. Neuropharmacology. 2008. PMID: 18761360 Review.
Cited by
- Expression of brain-derived neurotrophic factor, IGF-1 and cortisol elicited by regular aerobic exercise in adolescents.
Jeon YK, Ha CH. Jeon YK, et al. J Phys Ther Sci. 2015 Mar;27(3):737-41. doi: 10.1589/jpts.27.737. Epub 2015 Mar 31. J Phys Ther Sci. 2015. PMID: 25931720 Free PMC article. - The effects of aerobic exercise intensity and duration on levels of brain-derived neurotrophic factor in healthy men.
Schmolesky MT, Webb DL, Hansen RA. Schmolesky MT, et al. J Sports Sci Med. 2013 Sep 1;12(3):502-11. eCollection 2013. J Sports Sci Med. 2013. PMID: 24149158 Free PMC article. - Peripheral BDNF Response to Physical and Cognitive Exercise and Its Association With Cardiorespiratory Fitness in Healthy Older Adults.
Tarassova O, Ekblom MM, Moberg M, Lövdén M, Nilsson J. Tarassova O, et al. Front Physiol. 2020 Aug 25;11:1080. doi: 10.3389/fphys.2020.01080. eCollection 2020. Front Physiol. 2020. PMID: 32982796 Free PMC article. - Physical exercise as a preventive or disease-modifying treatment of dementia and brain aging.
Ahlskog JE, Geda YE, Graff-Radford NR, Petersen RC. Ahlskog JE, et al. Mayo Clin Proc. 2011 Sep;86(9):876-84. doi: 10.4065/mcp.2011.0252. Mayo Clin Proc. 2011. PMID: 21878600 Free PMC article. Review. - Changes in serum BDNF levels associated with moderate-intensity exercise in healthy young Japanese men.
Goda A, Ohgi S, Kinpara K, Shigemori K, Fukuda K, Schneider EB. Goda A, et al. Springerplus. 2013 Dec 18;2:678. doi: 10.1186/2193-1801-2-678. eCollection 2013. Springerplus. 2013. PMID: 24386624 Free PMC article.
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Medical