Viral diversity and dynamics in an infant gut - PubMed (original) (raw)
. 2008 Jun;159(5):367-73.
doi: 10.1016/j.resmic.2008.04.006. Epub 2008 May 1.
Matthew Haynes, Scott Kelley, Florent Angly, Robert A Edwards, Ben Felts, Joseph M Mahaffy, Jennifer Mueller, James Nulton, Steve Rayhawk, Beltran Rodriguez-Brito, Peter Salamon, Forest Rohwer
Affiliations
- PMID: 18541415
- DOI: 10.1016/j.resmic.2008.04.006
Free article
Viral diversity and dynamics in an infant gut
Mya Breitbart et al. Res Microbiol. 2008 Jun.
Free article
Abstract
Metagenomic sequencing of DNA viruses from the feces of a healthy week-old infant revealed a viral community with extremely low diversity. The identifiable sequences were dominated by phages, which likely influence the diversity and abundance of co-occurring microbes. The most abundant fecal viral sequences did not originate from breast milk or formula, suggesting a non-dietary initial source of viruses. Certain sequences were stable in the infant's gut over the first 3 months of life, but microarray experiments demonstrated that the overall viral community composition changed dramatically between 1 and 2 weeks of age.
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