Pyrazole inhibitors of coactivator associated arginine methyltransferase 1 (CARM1) - PubMed (original) (raw)
. 2008 Aug 1;18(15):4438-41.
doi: 10.1016/j.bmcl.2008.06.026. Epub 2008 Jun 12.
Affiliations
- PMID: 18619839
- DOI: 10.1016/j.bmcl.2008.06.026
Pyrazole inhibitors of coactivator associated arginine methyltransferase 1 (CARM1)
Ashok V Purandare et al. Bioorg Med Chem Lett. 2008.
Abstract
This study reports the identification and Hits to Leads optimization of inhibitors of coactivator associated arginine methyltransferase (CARM1). Compound 7b is a potent, selective inhibitor of CARM1.
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