Lowering HbA1c in type 2 diabetics results in reduced risk of coronary heart disease and all-cause mortality - PubMed (original) (raw)
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Lowering HbA1c in type 2 diabetics results in reduced risk of coronary heart disease and all-cause mortality
Rien ten Brinke et al. Prim Care Diabetes. 2008 Feb.
Abstract
Aims: To assess to which extent lowering the level of HbA1c influences the 10-year risk of coronary heart disease (CHD) and all-cause mortality in patients with type 2 diabetes mellitus.
Methods: A literature search in Pubmed and Embase was performed, and the absolute risks in the results of the relevant and valid studies compared.
Results: Each study shows that with a decreasing percentage of HbA1c, both the risk of developing CHD and the risk of mortality decrease.
Conclusions: Lowering HbA1c in type 2 diabetics decreases the absolute risk of developing CHD by 5-17%, as well as decreasing all-cause mortality by 6-15%.
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