Analysis of mortality rates for pancreatic cancer across the world - PubMed (original) (raw)
Analysis of mortality rates for pancreatic cancer across the world
D Hariharan et al. HPB (Oxford). 2008.
Abstract
Introduction: Pancreas cancer is the fourth commonest cause of cancer-related mortality across the world, with incidence equalling mortality. A recent study has suggested that both the incidence and the mortality of pancreatic cancer are falling in the UK. We investigated whether this trend was being seen all over the world.
Methods: Age-standardized mortality (world) rates [ASR(W)] for pancreatic cancer were extracted separately for males and females from a database maintained by the International Agency for Research on Cancer for 51 countries across the world (Europe, 33 countries; Americas, 8 countries; and Asia, 10 countries) for the period 1992-2002; log-linear regression analysis was performed to analyse trends in the past decade.
Results: In the period 1992-2002, the ASR(W) remained static across most countries for both sexes. The highest mortality rates (for both sexes) were seen in Central Europe [range: men (8-12), women (4.5-7)] with trends towards increasing mortality in Romania (p<0.001), along with Albania, Spain and Croatia (p<0.01). Korea in the Far East, too, demonstrated increasing mortality trends for both sexes (men p<0.001, women p<0.01). Increasing mortality trends were also observed among women in France (p<0.001). In Canada, there was a decline in mortality [men (7.5-6.4), women (5.9-5); p<0.01], while for men there was a downward trend in Ireland, the UK, Switzerland, Austria, and Poland [p<0.05].
Conclusion: The changes perhaps reflect standardization and consolidation of diagnostic tests for pancreatic cancer in the Western world and further in-depth analysis would be required.
Keywords: Age standardized mortality; pancreatic cancer; trends.
Figures
Figure 1.
Mortality (ASR(W)) due to pancreatic cancer in males in Southern Europe during the period 1992–2002, smoothed using quadratic regression.
Figure 2.
Mortality (ASR(W)) due to pancreatic cancer in females in Southern Europe during the period 1992–2002, smoothed using quadratic regression.
Similar articles
- Analysis of mortality rates for gallbladder cancer across the world.
Hariharan D, Saied A, Kocher HM. Hariharan D, et al. HPB (Oxford). 2008;10(5):327-31. doi: 10.1080/13651820802007464. HPB (Oxford). 2008. PMID: 18982147 Free PMC article. - International patterns in incidence and mortality trends of pancreatic cancer in the last three decades: A joinpoint regression analysis.
Ilic I, Ilic M. Ilic I, et al. World J Gastroenterol. 2022 Aug 28;28(32):4698-4715. doi: 10.3748/wjg.v28.i32.4698. World J Gastroenterol. 2022. PMID: 36157927 Free PMC article. - Prostate cancer incidence and mortality trends among elderly and adult Europeans.
Vercelli M, Quaglia A, Marani E, Parodi S. Vercelli M, et al. Crit Rev Oncol Hematol. 2000 Aug;35(2):133-44. doi: 10.1016/s1040-8428(99)00067-0. Crit Rev Oncol Hematol. 2000. PMID: 10936470 - Global incidence and outcome of testicular cancer.
Shanmugalingam T, Soultati A, Chowdhury S, Rudman S, Van Hemelrijck M. Shanmugalingam T, et al. Clin Epidemiol. 2013 Oct 17;5:417-27. doi: 10.2147/CLEP.S34430. Clin Epidemiol. 2013. PMID: 24204171 Free PMC article. Review. - Ovarian and endometrial cancers.
Mant JW, Vessey MP. Mant JW, et al. Cancer Surv. 1994;19-20:287-307. Cancer Surv. 1994. PMID: 7895220 Review.
Cited by
- Silencing of the integrin-linked kinase gene suppresses the proliferation, migration and invasion of pancreatic cancer cells (Panc-1).
Zhu XY, Liu N, Liu W, Song SW, Guo KJ. Zhu XY, et al. Genet Mol Biol. 2012 Apr;35(2):538-44. doi: 10.1590/S1415-47572012005000028. Epub 2012 May 17. Genet Mol Biol. 2012. PMID: 22888305 Free PMC article. - Imaging and Therapy of Pancreatic Cancer with Phosphatidylserine-Targeted Nanovesicles.
Blanco VM, Latif T, Chu Z, Qi X. Blanco VM, et al. Transl Oncol. 2015 Jun;8(3):196-203. doi: 10.1016/j.tranon.2015.03.011. Transl Oncol. 2015. PMID: 26055177 Free PMC article. Review. - Randomized trial comparing the 22-gauge aspiration and 22-gauge biopsy needles for EUS-guided sampling of solid pancreatic mass lesions.
Bang JY, Hebert-Magee S, Trevino J, Ramesh J, Varadarajulu S. Bang JY, et al. Gastrointest Endosc. 2012 Aug;76(2):321-7. doi: 10.1016/j.gie.2012.03.1392. Epub 2012 May 31. Gastrointest Endosc. 2012. PMID: 22658389 Free PMC article. Clinical Trial. - Long-term survival in a cat with pancreatic adenocarcinoma treated with surgical resection and toceranib phosphate.
Todd JE, Nguyen SM. Todd JE, et al. JFMS Open Rep. 2020 Jun 12;6(1):2055116920924911. doi: 10.1177/2055116920924911. eCollection 2020 Jan-Jun. JFMS Open Rep. 2020. PMID: 32587749 Free PMC article. - Accomplishments in 2008 in the management of localized pancreatic cancer.
O'Reilly EM, Lutz MP, Neuhaus P. O'Reilly EM, et al. Gastrointest Cancer Res. 2009 Sep;3(5 Supplement 2):S37-42. Gastrointest Cancer Res. 2009. PMID: 20011563 Free PMC article.
References
- Alexakis N, Halloran C, Raraty M, Ghaneh P, Sutton R, Neoptolemos JP. Current standards of surgery for pancreatic cancer. Br J Surg. 2004;91:1410–27. - PubMed
- Jemal A, Siegel R, Ward E, Murray T, Xu J, Thun MJ. Cancer statistics, 2007. CA Cancer J Clin. 2007;57:43–66. - PubMed
- Lowenfels AB, Maisonneuve P. Epidemiology and risk factors for pancreatic cancer. Best Pract Res Clin Gastroenterol. 2006;20:197–209. - PubMed
- O'Sullivan A, Kocher HM. Pancreatic cancer. Br Med J Clin Evid. 2007;11:409–37. - PubMed
- Li D, Xie K, Wolff R, Abbruzzese JL. Pancreatic cancer. Lancet. 2004;363(9414):1049–57. - PubMed
LinkOut - more resources
Full Text Sources
Other Literature Sources
Miscellaneous