Incidence of Wegener's granulomatosis in Finland 1981-2000 - PubMed (original) (raw)
. 2008 May-Jun;26(3 Suppl 49):S81-5.
Affiliations
- PMID: 18799060
Incidence of Wegener's granulomatosis in Finland 1981-2000
J H Takala et al. Clin Exp Rheumatol. 2008 May-Jun.
Abstract
Objective: To determine the incidence and clinical presentation of Wegener's granulomatosis (WG) in Finland during the 20-year period 1981-2000.
Methods: We performed a study with retrospective data retrieval using the hospital discharge register in Finland. All available hospital case reports were reviewed. We included those patients diagnosed with and treated for WG. Demographic and clinical data at diagnosis were recorded.
Results: Of the 492 patients diagnosed with WG, 49% were male. Mean age at diagnosis was 53.2 years (SD 18.1). The highest rate of incidence occurred in men and women aged 65-74 years. The annual incidence per million of the population increased from 1.9 (95% CI 1.4 to 2.6) during 1981-1985 to 9.3 (95% CI 8.1 to 10.6) during 1996-2000 with gender age-adjusted incidence rate ratio 4.5 (CI 3.6 to 5.7). Only minor changes in the signs and symptoms at diagnosis occurred during the 20-year span. In 83% of cases, the ACR criteria (>or=2 criteria) were fulfilled. The mean age at diagnosis rose from 45.8 to 55.0 years and the median diagnostic delay decreased from 17 to 4 months during the two decades.
Conclusion: The incidence of WG has increased during the last two decades with little change in clinical symptoms at presentation. At the same time, the mean age of the patients has increased and the diagnostic delay has considerably shortened.
Similar articles
- Epidemiology of Wegener's granulomatosis in northern Norway.
Koldingsnes W, Nossent H. Koldingsnes W, et al. Arthritis Rheum. 2000 Nov;43(11):2481-7. doi: 10.1002/1529-0131(200011)43:11<2481::AID-ANR15>3.0.CO;2-6. Arthritis Rheum. 2000. PMID: 11083271 - Epidemiology of granulomatosis with polyangiitis (Wegener's granulomatosis) in Northern Italy: a 15-year population-based study.
Catanoso M, Macchioni P, Boiardi L, Manenti L, Tumiati B, Cavazza A, Luberto F, Pipitone N, Salvarani C. Catanoso M, et al. Semin Arthritis Rheum. 2014 Oct;44(2):202-7. doi: 10.1016/j.semarthrit.2014.05.005. Epub 2014 May 9. Semin Arthritis Rheum. 2014. PMID: 24932888 - Prevalence and incidence of Wegener's granulomatosis in the UK general practice research database.
Watts RA, Al-Taiar A, Scott DG, Macgregor AJ. Watts RA, et al. Arthritis Rheum. 2009 Oct 15;61(10):1412-6. doi: 10.1002/art.24544. Arthritis Rheum. 2009. PMID: 19790134 - [Wegener's granulomatosis. Report of a pediatric case and review of the literature].
Ayala de la Cruz Mdel C, González Díaz R, López Lara ND. Ayala de la Cruz Mdel C, et al. Rev Alerg Mex. 2003 Mar-Apr;50(2):71-5. Rev Alerg Mex. 2003. PMID: 12825492 Review. Spanish. - [Incidence and presentation of the central neurological manifestations of Wegener's granulomatosis: a monocentric study of 14 cases].
Konaté A, Le Falher G, Crozat-Grosleron S, Rivière S, Le Quellec A. Konaté A, et al. Rev Med Interne. 2004 Mar;25(3):183-8. doi: 10.1016/S0248-8663(03)00266-2. Rev Med Interne. 2004. PMID: 14990292 Review. French.
Cited by
- Antineutrophil Cytoplasmic Antibody-Associated Vasculitis and the Risk of Developing Incidental Tuberculosis: A Population-Based Cohort Study.
Chan SH, Li MF, Ou SH, Lin MC, Wang JH, Lee PT, Chen HY. Chan SH, et al. Medicina (Kaunas). 2023 Oct 30;59(11):1920. doi: 10.3390/medicina59111920. Medicina (Kaunas). 2023. PMID: 38003970 Free PMC article. - Stable incidence but increase in prevalence of ANCA-associated vasculitis in southern Sweden: a 23-year study.
Rathmann J, Segelmark M, Englund M, Mohammad AJ. Rathmann J, et al. RMD Open. 2023 Mar;9(1):e002949. doi: 10.1136/rmdopen-2022-002949. RMD Open. 2023. PMID: 36894194 Free PMC article. - Global epidemiology of vasculitis.
Watts RA, Hatemi G, Burns JC, Mohammad AJ. Watts RA, et al. Nat Rev Rheumatol. 2022 Jan;18(1):22-34. doi: 10.1038/s41584-021-00718-8. Epub 2021 Dec 1. Nat Rev Rheumatol. 2022. PMID: 34853411 Free PMC article. Review. - Temporal and Cartographic Analyses of the Distribution within Spain of Mortality Due to Granulomatosis with Polyangiitis (1984⁻2016).
Sánchez-Díaz G, Escobar F, Villaverde-Hueso A, de la Paz MP, Alonso-Ferreira V. Sánchez-Díaz G, et al. Int J Environ Res Public Health. 2019 Apr 17;16(8):1388. doi: 10.3390/ijerph16081388. Int J Environ Res Public Health. 2019. PMID: 30999675 Free PMC article. - Epidemiology and Outcomes of Granulomatosis With Polyangiitis in Pediatric and Working-Age Adult Populations In the United States: Analysis of a Large National Claims Database.
Panupattanapong S, Stwalley DL, White AJ, Olsen MA, French AR, Hartman ME. Panupattanapong S, et al. Arthritis Rheumatol. 2018 Dec;70(12):2067-2076. doi: 10.1002/art.40577. Arthritis Rheumatol. 2018. PMID: 29806148 Free PMC article.
Publication types
MeSH terms
LinkOut - more resources
Full Text Sources
Medical