Suramin: clinical uses and structure-activity relationships - PubMed (original) (raw)

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Suramin: clinical uses and structure-activity relationships

Ross P McGeary et al. Mini Rev Med Chem. 2008 Nov.

Abstract

Suramin is a polysulfonated polyaromatic symmetrical urea. It is currently used to treat African river blindness and African sleeping sickness. Suramin has also been extensively trialed recently to treat a number of other diseases, including many cancers. Here, we examine its modes of action and discuss its structure-activity relationships.

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