Genome-scale analyses of health-promoting bacteria: probiogenomics - PubMed (original) (raw)

Review

doi: 10.1038/nrmicro2047. Epub 2008 Nov 24.

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Review

Genome-scale analyses of health-promoting bacteria: probiogenomics

Marco Ventura et al. Nat Rev Microbiol. 2009 Jan.

Abstract

The human body is colonized by an enormous population of bacteria (microbiota) that provides the host with coding capacity and metabolic activities. Among the human gut microbiota are health-promoting indigenous species (probiotic bacteria) that are commonly consumed as live dietary supplements. Recent genomics-based studies (probiogenomics) are starting to provide insights into how probiotic bacteria sense and adapt to the gastrointestinal tract environment. In this Review, we discuss the application of probiogenomics in the elucidation of the molecular basis of probiosis using the well-recognized model probiotic bacteria genera Bifidobacterium and Lactobacillus as examples.

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References

    1. J Clin Invest. 1985 Mar;75(3):944-53 - PubMed
    1. Proc Natl Acad Sci U S A. 2005 Mar 15;102(11):3906-12 - PubMed
    1. Appl Environ Microbiol. 2000 Jun;66(6):2578-88 - PubMed
    1. Appl Environ Microbiol. 2005 Jul;71(7):3475-82 - PubMed
    1. Int J Syst Evol Microbiol. 2008 Dec;58(Pt 12):2945-54 - PubMed

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