Peroxisome proliferator-activated receptor alpha and the ketogenic diet - PubMed (original) (raw)

Review

Peroxisome proliferator-activated receptor alpha and the ketogenic diet

Tim Cullingford. Epilepsia. 2008 Nov.

Abstract

Peroxisome proliferator-activated receptor alpha (PPARalpha) is a drug/fatty acid-activated trans cription factor involved in the starvation response, and is thus relevant to the ketogenic diet (KD). This article summarizes research indicating the role of PPARalpha in central and peripheral nervous system function with particular reference to downstream targets relevant to anticonvulsant action.

PubMed Disclaimer

Publication types

MeSH terms

Substances

LinkOut - more resources