Free left arms as precursor molecules in the evolution of Alu sequences - PubMed (original) (raw)

Free left arms as precursor molecules in the evolution of Alu sequences

J Jurka et al. J Mol Evol. 1991 Jul.

Abstract

The dimeric Alu molecule of human and other primates is composed of a left and a right arm that are very similar but show characteristic differences. If the Alu sequence has arisen through the fusion of monomeric precursor molecules, the traces of such precursor genes are expected still to be present in contemporary primate DNA. We report finding seven independent human DNA sequences that qualify as descendants of a left-arm precursor gene. Some characteristics in primary and secondary structures of these sequences are described.

PubMed Disclaimer

Similar articles

• Fusion of a free left Alu monomer and a free right Alu monomer at the origin of the Alu family in the primate genomes.
  Quentin Y. Quentin Y. Nucleic Acids Res. 1992 Feb 11;20(3):487-93. doi: 10.1093/nar/20.3.487. Nucleic Acids Res. 1992. PMID: 1741283 Free PMC article.
• Monophyletic origin of Alu elements in primates.
  Zietkiewicz E, Richer C, Sinnett D, Labuda D. Zietkiewicz E, et al. J Mol Evol. 1998 Aug;47(2):172-82. doi: 10.1007/pl00006374. J Mol Evol. 1998. PMID: 9694666
• Origin of the Alu family: a family of Alu-like monomers gave birth to the left and the right arms of the Alu elements.
  Quentin Y. Quentin Y. Nucleic Acids Res. 1992 Jul 11;20(13):3397-401. doi: 10.1093/nar/20.13.3397. Nucleic Acids Res. 1992. PMID: 1378589 Free PMC article.
• Emergence of master sequences in families of retroposons derived from 7sl RNA.
  Quentin Y. Quentin Y. Genetica. 1994;93(1-3):203-15. doi: 10.1007/BF01435252. Genetica. 1994. PMID: 7529207 Review.
• The Alu family of dispersed repetitive sequences.
  Schmid CW, Jelinek WR. Schmid CW, et al. Science. 1982 Jun 4;216(4550):1065-70. doi: 10.1126/science.6281889. Science. 1982. PMID: 6281889 Review.

Cited by

• Monomeric scAlu and nascent dimeric Alu RNAs induced by adenovirus are assembled into SRP9/14-containing RNPs in HeLa cells.
  Chang DY, Hsu K, Maraia RJ. Chang DY, et al. Nucleic Acids Res. 1996 Nov 1;24(21):4165-70. doi: 10.1093/nar/24.21.4165. Nucleic Acids Res. 1996. PMID: 8932367 Free PMC article.
• The SRP9/14 subunit of the human signal recognition particle binds to a variety of Alu-like RNAs and with higher affinity than its mouse homolog.
  Bovia F, Wolff N, Ryser S, Strub K. Bovia F, et al. Nucleic Acids Res. 1997 Jan 15;25(2):318-26. doi: 10.1093/nar/25.2.318. Nucleic Acids Res. 1997. PMID: 9016560 Free PMC article.
• A SINE in the genome of the cephalochordate amphioxus is an Alu element.
  Holland LZ. Holland LZ. Int J Biol Sci. 2006;2(2):61-5. doi: 10.7150/ijbs.2.61. Epub 2006 Apr 10. Int J Biol Sci. 2006. PMID: 16733535 Free PMC article.
• Identification of splicing silencers and enhancers in sense Alus: a role for pseudoacceptors in splice site repression.
  Lei H, Vorechovsky I. Lei H, et al. Mol Cell Biol. 2005 Aug;25(16):6912-20. doi: 10.1128/MCB.25.16.6912-6920.2005. Mol Cell Biol. 2005. PMID: 16055705 Free PMC article.
• Evolution of secondary structure in the family of 7SL-like RNAs.
  Labuda D, Zietkiewicz E. Labuda D, et al. J Mol Evol. 1994 Nov;39(5):506-18. doi: 10.1007/BF00173420. J Mol Evol. 1994. PMID: 7528809

References

1. 1. Mol Biol Evol. 1988 Jan;5(1):97-108 - PubMed
2. 1. Proc Natl Acad Sci U S A. 1989 May;86(10):3718-22 - PubMed
3. 1. J Mol Evol. 1987;26(3):180-6 - PubMed
4. 1. Int Rev Cytol. 1985;93:187-279 - PubMed
5. 1. Mol Biol Evol. 1987 Jan;4(1):19-29 - PubMed

Publication types

MeSH terms

Substances