RNA silencing in germlines--exquisite collaboration of Argonaute proteins with small RNAs for germline survival - PubMed (original) (raw)
Review
RNA silencing in germlines--exquisite collaboration of Argonaute proteins with small RNAs for germline survival
Mikiko C Siomi et al. Curr Opin Cell Biol. 2009 Jun.
Abstract
As the proper development of germlines is vital for species preservation, elaborative, regulatory systems for gene expression must operate in germlines. One such system is RNA silencing, sequence-specific gene silencing mechanisms mediated by small RNAs of 20-30 nucleotides long. Indeed, recent studies have revealed that various types of small RNAs are expressed germline-specifically. To preserve the germlines, they collaborate with Argonaute proteins, the catalytic engines in RNA silencing, to inhibit injurious, parasitic genes, transcriptionally or post-transcriptionally. This chapter summarizes the exquisite collaboration of Argonaute proteins with small RNAs in the RNA silencing mechanisms necessary for germline survival in Drosophila and mice.
Similar articles
- Argonaute proteins: mediators of RNA silencing.
Peters L, Meister G. Peters L, et al. Mol Cell. 2007 Jun 8;26(5):611-23. doi: 10.1016/j.molcel.2007.05.001. Mol Cell. 2007. PMID: 17560368 Review. - Small RNAs just got bigger: Piwi-interacting RNAs (piRNAs) in mammalian testes.
Kim VN. Kim VN. Genes Dev. 2006 Aug 1;20(15):1993-7. doi: 10.1101/gad.1456106. Genes Dev. 2006. PMID: 16882976 Review. - The growing catalog of small RNAs and their association with distinct Argonaute/Piwi family members.
Farazi TA, Juranek SA, Tuschl T. Farazi TA, et al. Development. 2008 Apr;135(7):1201-14. doi: 10.1242/dev.005629. Epub 2008 Feb 20. Development. 2008. PMID: 18287206 Review. - Chapter 16. How to define targets for small guide RNAs in RNA silencing: a biochemical approach.
Siomi MC, Nishida KM, Siomi H. Siomi MC, et al. Methods Enzymol. 2008;449:345-55. doi: 10.1016/S0076-6879(08)02416-6. Methods Enzymol. 2008. PMID: 19215766 - The coming of age for Piwi proteins.
Seto AG, Kingston RE, Lau NC. Seto AG, et al. Mol Cell. 2007 Jun 8;26(5):603-9. doi: 10.1016/j.molcel.2007.05.021. Mol Cell. 2007. PMID: 17560367 Review.
Cited by
- Small RNAs in the animal gonad: guarding genomes and guiding development.
Lau NC. Lau NC. Int J Biochem Cell Biol. 2010 Aug;42(8):1334-47. doi: 10.1016/j.biocel.2010.03.005. Epub 2010 Mar 19. Int J Biochem Cell Biol. 2010. PMID: 20227517 Free PMC article. Review. - Programmed DNA elimination in Tetrahymena: a small RNA-mediated genome surveillance mechanism.
Kataoka K, Mochizuki K. Kataoka K, et al. Adv Exp Med Biol. 2011;722:156-73. doi: 10.1007/978-1-4614-0332-6_10. Adv Exp Med Biol. 2011. PMID: 21915788 Free PMC article. Review. - ADAD2 functions in spermiogenesis and piRNA biogenesis in mice.
Lu Y, Nagamori I, Kobayashi H, Kojima-Kita K, Shirane K, Chang HY, Nishimura T, Koyano T, Yu Z, Castañeda JM, Matsuyama M, Kuramochi-Miyagawa S, Matzuk MM, Ikawa M. Lu Y, et al. Andrology. 2023 May;11(4):698-709. doi: 10.1111/andr.13400. Epub 2023 Feb 14. Andrology. 2023. PMID: 36698249 Free PMC article. - Biogenesis pathways of piRNAs loaded onto AGO3 in the Drosophila testis.
Nagao A, Mituyama T, Huang H, Chen D, Siomi MC, Siomi H. Nagao A, et al. RNA. 2010 Dec;16(12):2503-15. doi: 10.1261/rna.2270710. Epub 2010 Oct 27. RNA. 2010. PMID: 20980675 Free PMC article. - Knockout Gene-Based Evidence for PIWI-Interacting RNA Pathway in Mammals.
Li Y, Zhang Y, Liu M. Li Y, et al. Front Cell Dev Biol. 2021 Jul 14;9:681188. doi: 10.3389/fcell.2021.681188. eCollection 2021. Front Cell Dev Biol. 2021. PMID: 34336834 Free PMC article. Review.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Molecular Biology Databases
Research Materials