G protein-coupled receptor 30: estrogen receptor or collaborator? - PubMed (original) (raw)

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G protein-coupled receptor 30: estrogen receptor or collaborator?

Ellis R Levin. Endocrinology. 2009 Apr.

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Figure 1

Possible collaboration between GPR30 and membrane ERα. GPR30 may transmit early signals from membrane ERα in cancer cells to downstream signal molecules (e.g. growth factor receptors). This occurs in cell and context-specific fashion for some signal cascades that modulate cell biology. MNAR, Modulator of nongenomic activity of estrogen receptor; PI3K, PI3 kinase; PKC, protein kinase C; PLC, phospholipase C.

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