J1-M267 Y lineage marks climate-driven pre-historical human displacements - PubMed (original) (raw)

. 2009 Nov;17(11):1520-4.

doi: 10.1038/ejhg.2009.58. Epub 2009 Apr 15.

Gianmarco Ferri, Kazima Bulayeva, Laura Caciagli, Valerio Onofri, Luca Taglioli, Oleg Bulayev, Ilaria Boschi, Milena Alù, Andrea Berti, Cesare Rapone, Giovanni Beduschi, Donata Luiselli, Alicia M Cadenas, Khalid Dafaallah Awadelkarim, Renato Mariani-Costantini, Nasr Eldin Elwali, Fabio Verginelli, Elena Pilli, Rene J Herrera, Leonor Gusmão, Giorgio Paoli, Cristian Capelli

Affiliations

PMID: 19367321
PMCID: PMC2986692
DOI: 10.1038/ejhg.2009.58

J1-M267 Y lineage marks climate-driven pre-historical human displacements

Sergio Tofanelli et al. Eur J Hum Genet. 2009 Nov.

Abstract

The present day distribution of Y chromosomes bearing the haplogroup J1 M267(*)G variant has been associated with different episodes of human demographic history, the main one being the diffusion of Islam since the Early Middle Ages. To better understand the modes and timing of J1 dispersals, we reconstructed the genealogical relationships among 282 M267(*)G chromosomes from 29 populations typed at 20 YSTRs and 6 SNPs. Phylogenetic analyses depicted a new genetic background consistent with climate-driven demographic dynamics occurring during two key phases of human pre-history: (1) the spatial expansion of hunter gatherers in response to the end of the late Pleistocene cooling phases and (2) the displacement of groups of foragers/herders following the mid-Holocene rainfall retreats across the Sahara and Arabia. Furthermore, J1 STR motifs previously used to trace Arab or Jewish ancestries were shown unsuitable as diagnostic markers for ethnicity.

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Figures

Figure 1

Contour map showing the present day distribution of J1 and J*(xJ2) chromosomes. Gridding was carried out starting from 336 frequency points (Supplementary Table S3) with SURFIT 2.1 (

http://surfit.sourceforge.net/index.html

). Spatial surfaces were computed using GMT 4.3.1 (

http://gmt.soest.hawaii.edu

). Methodological details are available on request.

Figure 2

MDS plot of pairwise _F_ST distances among 18–locus haplotypes (alleles at duplicated loci Dys385a/b and YCAIIa/b were pooled). Stress value (0.07775) denotes a statistically significant departure from random structure. Dots colour: light blue=Dagestan groups, black=Arabian groups, Grey=Maghrebian groups, Purple=Sudanese groups, Green=European groups, Orange=SW Asian groups, Yellow=Ethiopian groups. Dots' shape: squares=Arabic-speaking groups; circles=Indo-European-speaking groups; diamonds=North-Caucasian-speaking groups; triangle=Semitic (non-Arabic)-speaking groups (the colour reproduction of this figure is available on the full text version of the manuscript).

Figure 3

Network of 20-locus J1 haplotypes. (a) Arabic pool genealogy, (b) Eurasian pool genealogy. Area is proportional to frequency (the colour reproduction of this figure is available on the full text version of the manuscript).

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