Small fiber neuropathy: A burning problem - PubMed (original) (raw)
Review
. 2009 May;76(5):297-305.
doi: 10.3949/ccjm.76a.08070.
Affiliations
- PMID: 19414545
- DOI: 10.3949/ccjm.76a.08070
Free article
Review
Small fiber neuropathy: A burning problem
Jinny Tavee et al. Cleve Clin J Med. 2009 May.
Free article
Abstract
Small fiber neuropathy is increasingly being recognized as a major cause of painful burning sensations in the feet, especially in the elderly. Although strength remains preserved throughout the course of the disease, the pain and paresthesias are often disabling. Diabetes mellitus is the most common identifiable cause of small fiber neuropathy, and impaired oral glucose tolerance and individual components of the metabolic syndrome are often associated with it. Some cases, however, are idiopathic. Skin biopsy (with an evaluation of the density of intraepidermal nerve fibers) and tests of autonomic nerve function are useful for the diagnosis. Management involves controlling pain and identifying and aggressively treating the underlying cause.
Similar articles
- Small-fiber neuropathy.
Lacomis D. Lacomis D. Muscle Nerve. 2002 Aug;26(2):173-88. doi: 10.1002/mus.10181. Muscle Nerve. 2002. PMID: 12210380 Review. - Small-fiber neuropathy: answering the burning questions.
Fink E, Oaklander AL. Fink E, et al. Sci Aging Knowledge Environ. 2006 Mar 8;2006(6):pe7. doi: 10.1126/sageke.2006.6.pe7. Sci Aging Knowledge Environ. 2006. PMID: 16525192 Review. - [Confirmation of the use of skin biopsy in small-fiber neuropathy. First results].
Collongues N, Blanc F, Echaniz-Laguna A, Boehm N, de Seze J. Collongues N, et al. Rev Neurol (Paris). 2009 Mar;165(3):249-55. doi: 10.1016/j.neurol.2008.10.014. Epub 2008 Dec 3. Rev Neurol (Paris). 2009. PMID: 19056097 French. - Small-fiber sensory neuropathies: clinical course and neuropathology of idiopathic cases.
Holland NR, Crawford TO, Hauer P, Cornblath DR, Griffin JW, McArthur JC. Holland NR, et al. Ann Neurol. 1998 Jul;44(1):47-59. doi: 10.1002/ana.410440111. Ann Neurol. 1998. PMID: 9667592 Clinical Trial.
Cited by
- Sympathetic blocks provided sustained pain relief in a patient with refractory painful diabetic neuropathy.
Cheng J, Daftari A, Zhou L. Cheng J, et al. Case Rep Anesthesiol. 2012;2012:285328. doi: 10.1155/2012/285328. Epub 2012 Feb 6. Case Rep Anesthesiol. 2012. PMID: 22606406 Free PMC article. - Presence of onconeural antibodies in sarcoidosis patients with parasarcoidosis syndrome.
Lower EE, Sturdivant M, Baughman RP. Lower EE, et al. Sarcoidosis Vasc Diffuse Lung Dis. 2019;36(4):254-260. doi: 10.36141/svdld.v36i4.8745. Epub 2019 May 1. Sarcoidosis Vasc Diffuse Lung Dis. 2019. PMID: 32476961 Free PMC article. - Effects of low-level laser therapy on burning pain and quality of life in patients with burning mouth syndrome: a systematic review and meta-analysis.
Lu C, Yang C, Li X, Du G, Zhou X, Luo W, Du Q, Tang G. Lu C, et al. BMC Oral Health. 2023 Oct 9;23(1):734. doi: 10.1186/s12903-023-03441-w. BMC Oral Health. 2023. PMID: 37814265 Free PMC article. - I drank too much and now I can't walk: a case of alcohol-induced dysautonomia.
Assaker R, El Hasbani G, Antezana AA, Gamarra JV, Amaya-Suarez J, Bertely C, Suleman N. Assaker R, et al. Oxf Med Case Reports. 2021 Aug 13;2021(8):omab072. doi: 10.1093/omcr/omab072. eCollection 2021 Aug. Oxf Med Case Reports. 2021. PMID: 34408893 Free PMC article. - A Case of Autoimmune Small Fiber Neuropathy as Possible Post COVID Sequelae.
Panagiotides NG, Zimprich F, Machold K, Schlager O, Müller M, Ertl S, Löffler-Stastka H, Koppensteiner R, Wadowski PP. Panagiotides NG, et al. Int J Environ Res Public Health. 2023 Mar 10;20(6):4918. doi: 10.3390/ijerph20064918. Int J Environ Res Public Health. 2023. PMID: 36981826 Free PMC article.
Publication types
MeSH terms
LinkOut - more resources
Full Text Sources
Other Literature Sources
Medical