Micromanipulating cancer: microRNA-based therapeutics? - PubMed (original) (raw)

Review

. 2009 Jul-Aug;6(3):335-40.

doi: 10.4161/rna.6.3.9013. Epub 2009 Jul 14.

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Review

Micromanipulating cancer: microRNA-based therapeutics?

Fabio Petrocca et al. RNA Biol. 2009 Jul-Aug.

Abstract

Because microRNAs regulate cancer cell differentiation, proliferation, survival and metastasis, manipulating microRNA function, either by mimicking or inhibiting miRNAs implicated in cancer, could provide a powerful therapeutic strategy to interfere with key pathways for cancer progression. This review will explore some of the opportunities and obstacles to harnessing microRNA biology for cancer therapy.

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