Dynamic modeling of vaccinating behavior as a function of individual beliefs - PubMed (original) (raw)

Dynamic modeling of vaccinating behavior as a function of individual beliefs

Flávio Codeço Coelho et al. PLoS Comput Biol. 2009 Jul.

Abstract

Individual perception of vaccine safety is an important factor in determining a person's adherence to a vaccination program and its consequences for disease control. This perception, or belief, about the safety of a given vaccine is not a static parameter but a variable subject to environmental influence. To complicate matters, perception of risk (or safety) does not correspond to actual risk. In this paper we propose a way to include the dynamics of such beliefs into a realistic epidemiological model, yielding a more complete depiction of the mechanisms underlying the unraveling of vaccination campaigns. The methodology proposed is based on Bayesian inference and can be extended to model more complex belief systems associated with decision models. We found the method is able to produce behaviors which approximate what has been observed in real vaccine and disease scare situations. The framework presented comprises a set of useful tools for an adequate quantitative representation of a common yet complex public-health issue. These tools include representation of beliefs as Bayesian probabilities, usage of logarithmic pooling to combine probability distributions representing opinions, and usage of natural conjugate priors to efficiently compute the Bayesian posterior. This approach allowed a comprehensive treatment of the uncertainty regarding vaccination behavior in a realistic epidemiological model.

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Conflict of interest statement

The authors have declared that no competing interests exist.

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References

    1. Hennock EP. Vaccination policy against smallpox, 1835–1914: a comparison of England with Prussia and Imperial Germany. Soc Hist Med. 1998;11:49–71. - PubMed
    1. Ehreth J. The global value of vaccination. Vaccine. 2003;21:596–600. - PubMed
    1. Salmon DA, Teret SP, MacIntyre CR, Salisbury D, Burgess MA, et al. Compulsory vaccination and conscientious or philosophical exemptions: past, present, and future. Lancet. 2006;367:436–442. - PubMed
    1. Serpell L, Green J. Parental decision-making in childhood vaccination. Vaccine. 2006;24:4041–4046. - PubMed
    1. Camacho LAB. Yellow fever and public health in brazil. Cad Saúde Pública. 2008;24:482–483. - PubMed

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