Minisatellite repeat coding as a digital approach to DNA typing - PubMed (original) (raw)
. 1991 Nov 21;354(6350):204-9.
doi: 10.1038/354204a0.
Affiliations
- PMID: 1961248
- DOI: 10.1038/354204a0
Minisatellite repeat coding as a digital approach to DNA typing
A J Jeffreys et al. Nature. 1991.
Abstract
Most DNA typing systems used in forensic and legal medicine assay allelic length variation at tandem repetitive DNA regions such as minisatellites. A simple alternative approach that displays patterns of variant repeat units along minisatellite alleles is described here. This produces DNA profiles as extraordinarily variable digital sequences appropriate for forensic investigations, including computer databasing, and for analysing allele diversity and the role of recombination in minisatellite instability.
Comment in
- DNA fingerprinting. New variations on the theme.
Farr CJ, Goodfellow PN. Farr CJ, et al. Nature. 1991 Nov 21;354(6350):184. doi: 10.1038/354184a0. Nature. 1991. PMID: 1683683 No abstract available.
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