A neural mechanism for working and recognition memory in inferior temporal cortex - PubMed (original) (raw)
. 1991 Nov 29;254(5036):1377-9.
doi: 10.1126/science.1962197.
Affiliations
- PMID: 1962197
- DOI: 10.1126/science.1962197
A neural mechanism for working and recognition memory in inferior temporal cortex
E K Miller et al. Science. 1991.
Abstract
Inferior temporal (IT) cortex is critical for visual memory, but it is not known how IT neurons retain memories while new information is streaming into the visual system. Single neurons were therefore recorded from IT cortex of two rhesus monkeys performing tasks that required them to hold items in memory while concurrently viewing other items. The neuronal response to an incoming visual stimulus was attenuated if it matched a stimulus actively held in working memory, even when several other stimuli intervened. The neuronal response to novel stimuli declined as the stimuli became familiar to the animal. IT neurons appear to function as adaptive mnemonic "filters" that preferentially pass information about new, unexpected, or not recently seen stimuli.
Similar articles
- Responses of neurons in the inferior temporal cortex in short term and serial recognition memory tasks.
Baylis GC, Rolls ET. Baylis GC, et al. Exp Brain Res. 1987;65(3):614-22. doi: 10.1007/BF00235984. Exp Brain Res. 1987. PMID: 3556488 - Activity of neurons in anterior inferior temporal cortex during a short-term memory task.
Miller EK, Li L, Desimone R. Miller EK, et al. J Neurosci. 1993 Apr;13(4):1460-78. doi: 10.1523/JNEUROSCI.13-04-01460.1993. J Neurosci. 1993. PMID: 8463829 Free PMC article. - Role of inferior temporal neurons in visual memory. I. Temporal encoding of information about visual images, recalled images, and behavioral context.
Eskandar EN, Richmond BJ, Optican LM. Eskandar EN, et al. J Neurophysiol. 1992 Oct;68(4):1277-95. doi: 10.1152/jn.1992.68.4.1277. J Neurophysiol. 1992. PMID: 1432084 - Neural mechanisms for visual memory and their role in attention.
Desimone R. Desimone R. Proc Natl Acad Sci U S A. 1996 Nov 26;93(24):13494-9. doi: 10.1073/pnas.93.24.13494. Proc Natl Acad Sci U S A. 1996. PMID: 8942962 Free PMC article. Review. - Neural representation of visual objects: encoding and top-down activation.
Miyashita Y, Hayashi T. Miyashita Y, et al. Curr Opin Neurobiol. 2000 Apr;10(2):187-94. doi: 10.1016/s0959-4388(00)00071-4. Curr Opin Neurobiol. 2000. PMID: 10753793 Review.
Cited by
- Activation of the hippocampus in normal humans: a functional anatomical study of memory.
Squire LR, Ojemann JG, Miezin FM, Petersen SE, Videen TO, Raichle ME. Squire LR, et al. Proc Natl Acad Sci U S A. 1992 Mar 1;89(5):1837-41. doi: 10.1073/pnas.89.5.1837. Proc Natl Acad Sci U S A. 1992. PMID: 1542680 Free PMC article. - Manipulating attentional priority creates a trade-off between memory and sensory representations in human visual cortex.
Rademaker RL, Serences JT. Rademaker RL, et al. bioRxiv [Preprint]. 2024 Sep 16:2024.09.16.613302. doi: 10.1101/2024.09.16.613302. bioRxiv. 2024. PMID: 39345376 Free PMC article. Preprint. - Blockade of glutamatergic transmission in perirhinal cortex impairs object recognition memory in macaques.
Malkova L, Forcelli PA, Wellman LL, Dybdal D, Dubach MF, Gale K. Malkova L, et al. J Neurosci. 2015 Mar 25;35(12):5043-50. doi: 10.1523/JNEUROSCI.4307-14.2015. J Neurosci. 2015. PMID: 25810533 Free PMC article. - Neural correlates of olfactory recognition memory in the rat orbitofrontal cortex.
Ramus SJ, Eichenbaum H. Ramus SJ, et al. J Neurosci. 2000 Nov 1;20(21):8199-208. doi: 10.1523/JNEUROSCI.20-21-08199.2000. J Neurosci. 2000. PMID: 11050143 Free PMC article. - The role of the human hippocampus in familiarity-based and recollection-based recognition memory.
Wixted JT, Squire LR. Wixted JT, et al. Behav Brain Res. 2010 Dec 31;215(2):197-208. doi: 10.1016/j.bbr.2010.04.020. Epub 2010 Apr 20. Behav Brain Res. 2010. PMID: 20412819 Free PMC article. Review.
MeSH terms
LinkOut - more resources
Full Text Sources
Medical