Getting to the root of BRCA1-deficient breast cancer - PubMed (original) (raw)
. 2009 Sep 4;5(3):229-30.
doi: 10.1016/j.stem.2009.08.007.
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- PMID: 19733528
- DOI: 10.1016/j.stem.2009.08.007
Free article
Getting to the root of BRCA1-deficient breast cancer
Christophe Ginestier et al. Cell Stem Cell. 2009.
Free article
Abstract
Loss of BRCA1 has been shown to expand breast stem cells. In Nature Medicine, Lim et al. (2009) demonstrate that breast tissue from BRCA1 mutation carriers contains expanded luminal progenitor cells, suggesting a broader role for BRCA1 in mammary development.
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