TOR signaling in invertebrates - PubMed (original) (raw)

TOR signaling in invertebrates

Alexandre Soulard et al. Curr Opin Cell Biol. 2009 Dec.

Abstract

The Target of Rapamycin (TOR), a protein kinase, is the central node of a highly conserved signaling network that regulates cell growth in response to nutrients, hormones, and stresses. TOR is found in two functionally distinct complexes, TORC1 and TORC2. In this review we address the most recent advances in TOR signaling in invertebrate model organisms, including yeasts, plants, worms, and insects.

PubMed Disclaimer

Similar articles

• Complexity of the TOR signaling network.
  Inoki K, Guan KL. Inoki K, et al. Trends Cell Biol. 2006 Apr;16(4):206-12. doi: 10.1016/j.tcb.2006.02.002. Epub 2006 Mar 3. Trends Cell Biol. 2006. PMID: 16516475
• The expanding TOR signaling network.
  Martin DE, Hall MN. Martin DE, et al. Curr Opin Cell Biol. 2005 Apr;17(2):158-66. doi: 10.1016/j.ceb.2005.02.008. Curr Opin Cell Biol. 2005. PMID: 15780592 Review.
• mTOR in aging, metabolism, and cancer.
  Cornu M, Albert V, Hall MN. Cornu M, et al. Curr Opin Genet Dev. 2013 Feb;23(1):53-62. doi: 10.1016/j.gde.2012.12.005. Epub 2013 Jan 11. Curr Opin Genet Dev. 2013. PMID: 23317514 Review.
• mTOR-what does it do?
  Hall MN. Hall MN. Transplant Proc. 2008 Dec;40(10 Suppl):S5-8. doi: 10.1016/j.transproceed.2008.10.009. Transplant Proc. 2008. PMID: 19100909
• Nutritional control of cell growth via TOR signaling in budding yeast.
  Wei Y, Zheng XF. Wei Y, et al. Methods Mol Biol. 2011;759:307-19. doi: 10.1007/978-1-61779-173-4_18. Methods Mol Biol. 2011. PMID: 21863495 Review.

Cited by

• Deciphering the function and evolution of the target of rapamycin signaling pathway in microalgae.
  Mallén-Ponce MJ, Pérez-Pérez ME, Crespo JL. Mallén-Ponce MJ, et al. J Exp Bot. 2022 Nov 15;73(20):6993-7005. doi: 10.1093/jxb/erac264. J Exp Bot. 2022. PMID: 35710309 Free PMC article.
• Temperature-sensitive ipl1-2/Aurora B mutation is suppressed by mutations in TOR complex 1 via the Glc7/PP1 phosphatase.
  Tatchell K, Makrantoni V, Stark MJ, Robinson LC. Tatchell K, et al. Proc Natl Acad Sci U S A. 2011 Mar 8;108(10):3994-9. doi: 10.1073/pnas.1014406108. Epub 2011 Feb 22. Proc Natl Acad Sci U S A. 2011. PMID: 21368139 Free PMC article.
• A substrate localization model for the selective regulation of TORC1 downstream pathways.
  Takeda E, Matsuura A. Takeda E, et al. Commun Integr Biol. 2018 Jun 18;11(2):1-4. doi: 10.1080/19420889.2018.1475830. eCollection 2018. Commun Integr Biol. 2018. PMID: 30083287 Free PMC article.
• The susceptibility of trypanosomatid pathogens to PI3/mTOR kinase inhibitors affords a new opportunity for drug repurposing.
  Diaz-Gonzalez R, Kuhlmann FM, Galan-Rodriguez C, Madeira da Silva L, Saldivia M, Karver CE, Rodriguez A, Beverley SM, Navarro M, Pollastri MP. Diaz-Gonzalez R, et al. PLoS Negl Trop Dis. 2011 Aug;5(8):e1297. doi: 10.1371/journal.pntd.0001297. Epub 2011 Aug 23. PLoS Negl Trop Dis. 2011. PMID: 21886855 Free PMC article.
• Plant TOR signaling components.
  John F, Roffler S, Wicker T, Ringli C. John F, et al. Plant Signal Behav. 2011 Nov;6(11):1700-5. doi: 10.4161/psb.6.11.17662. Epub 2011 Nov 1. Plant Signal Behav. 2011. PMID: 22057328 Free PMC article. Review.

Publication types

MeSH terms

Substances

LinkOut - more resources

• Full Text Sources

  • ClinicalKey
  • Elsevier Science

• Molecular Biology Databases

  • Saccharomyces Genome Database