No way out for tumor cells - PubMed (original) (raw)
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. 2009 Oct 6;16(4):274-5.
doi: 10.1016/j.ccr.2009.09.021.
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- PMID: 19800571
- DOI: 10.1016/j.ccr.2009.09.021
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No way out for tumor cells
Conly L Rieder et al. Cancer Cell. 2009.
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Abstract
In this issue of Cancer Cell, Huang et al. report that preventing exit from mitosis provides a very efficient strategy for killing cells. Although this is not an unexpected finding, it nevertheless provides a novel conceptual framework for augmenting the antimitotic strategies currently under development for fighting cancer.
Comment on
- Evidence that mitotic exit is a better cancer therapeutic target than spindle assembly.
Huang HC, Shi J, Orth JD, Mitchison TJ. Huang HC, et al. Cancer Cell. 2009 Oct 6;16(4):347-58. doi: 10.1016/j.ccr.2009.08.020. Cancer Cell. 2009. PMID: 19800579 Free PMC article.
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