The follicular versus marginal zone B lymphocyte cell fate decision - PubMed (original) (raw)

Review

doi: 10.1038/nri2656.

Affiliations

• PMID: 19855403
• DOI: 10.1038/nri2656

Review

The follicular versus marginal zone B lymphocyte cell fate decision

Shiv Pillai et al. Nat Rev Immunol. 2009 Nov.

Abstract

Bone marrow-derived B cells make an important cell fate choice to develop into either follicular B cells or marginal zone B cells in the spleen, which depends on signalling through the B cell receptor, Notch2, the receptor for B cell-activating factor and the canonical nuclear factor-kappaB pathway, as well as signals involved in the migration and anatomical retention of marginal zone B cells. Recent information discussed in this Review reconciles some of the controversies regarding the role of the B cell receptor in this cell fate decision and a clearer picture has also emerged regarding the anatomical location of ligands for Notch2 in the spleen. This cell fate decision could provide mechanistic insights that are relevant to other commitment events in lymphocytes.

PubMed Disclaimer

Similar articles

• Signalling crosstalk in B cells: managing worth and need.
  Cancro MP. Cancro MP. Nat Rev Immunol. 2009 Sep;9(9):657-61. doi: 10.1038/nri2621. Nat Rev Immunol. 2009. PMID: 19704418 Free PMC article. Review.
• Positive selection and lineage commitment during peripheral B-lymphocyte development.
  Pillai S, Cariappa A, Moran ST. Pillai S, et al. Immunol Rev. 2004 Feb;197:206-18. doi: 10.1111/j.0105-2896.2003.097.x. Immunol Rev. 2004. PMID: 14962197 Review.
• Intrinsic molecular factors cause aberrant expansion of the splenic marginal zone B cell population in nonobese diabetic mice.
  Stolp J, Mariño E, Batten M, Sierro F, Cox SL, Grey ST, Silveira PA. Stolp J, et al. J Immunol. 2013 Jul 1;191(1):97-109. doi: 10.4049/jimmunol.1203252. Epub 2013 Jun 5. J Immunol. 2013. PMID: 23740954
• Notch2-mediated plasticity between marginal zone and follicular B cells.
  Lechner M, Engleitner T, Babushku T, Schmidt-Supprian M, Rad R, Strobl LJ, Zimber-Strobl U. Lechner M, et al. Nat Commun. 2021 Feb 17;12(1):1111. doi: 10.1038/s41467-021-21359-1. Nat Commun. 2021. PMID: 33597542 Free PMC article.
• Tonic B cell antigen receptor signals supply an NF-kappaB substrate for prosurvival BLyS signaling.
  Stadanlick JE, Kaileh M, Karnell FG, Scholz JL, Miller JP, Quinn WJ 3rd, Brezski RJ, Treml LS, Jordan KA, Monroe JG, Sen R, Cancro MP. Stadanlick JE, et al. Nat Immunol. 2008 Dec;9(12):1379-87. doi: 10.1038/ni.1666. Epub 2008 Nov 2. Nat Immunol. 2008. PMID: 18978795 Free PMC article.

Cited by

• Pediatric-type follicular lymphoma and pediatric nodal marginal zone lymphoma: additional evidence to support they are a single disease with variation in the histologic spectrum.
  Li HG, Jiang XN, Xue T, Xin BB, Chen L, Li GX, Wang Q, Hou QQ, Cai X, Zhou XY, Li XQ. Li HG, et al. Virchows Arch. 2024 Oct 8. doi: 10.1007/s00428-024-03941-2. Online ahead of print. Virchows Arch. 2024. PMID: 39379519
• Neu5Gc-mediated high-affinity interaction is dispensable for CD22 cis-ligands to regulate B cell signaling.
  Akatsu C, Naito-Matsui Y, Abdu-Allah HHM, Imamura A, Long W, Ishida H, Takematsu H, Tsubata T. Akatsu C, et al. J Biol Chem. 2024 Sep;300(9):107630. doi: 10.1016/j.jbc.2024.107630. Epub 2024 Aug 3. J Biol Chem. 2024. PMID: 39098526 Free PMC article.
• Immature B cell homing shapes human lymphoid tissue structure and function.
  Spencer J, Dionisi C. Spencer J, et al. J Exp Med. 2024 Sep 2;221(9):e20240085. doi: 10.1084/jem.20240085. Epub 2024 Aug 2. J Exp Med. 2024. PMID: 39093311 Free PMC article.
• Tipping the Scale: Atheroprotective IgM-Producing B Cells in Atherosclerosis.
  Ransegnola BP, Pattarabanjird T, McNamara CA. Ransegnola BP, et al. Arterioscler Thromb Vasc Biol. 2024 Sep;44(9):1906-1915. doi: 10.1161/ATVBAHA.124.319847. Epub 2024 Jul 18. Arterioscler Thromb Vasc Biol. 2024. PMID: 39022832 Review.
• Network Analysis of Osteoarthritis Progression Using a Steiner Minimal Tree Algorithm.
  Xie Y, Shao F, Ji Y, Feng D, Wang L, Huang Z, Wu S, Sun F, Jiang H, Miyamoto A, Wang H, Zhang C. Xie Y, et al. J Inflamm Res. 2024 May 18;17:3201-3209. doi: 10.2147/JIR.S438407. eCollection 2024. J Inflamm Res. 2024. PMID: 38779430 Free PMC article.

References

1. 1. Immunity. 2003 Jun;18(6):763-75 - PubMed
2. 1. Immunity. 2003 Feb;18(2):301-12 - PubMed
3. 1. Nat Immunol. 2000 Jul;1(1):31-6 - PubMed
4. 1. J Biol Chem. 2003 Oct 31;278(44):43654-62 - PubMed
5. 1. Trends Immunol. 2009 Oct;30(10):488-93 - PubMed

Publication types

MeSH terms

Substances

LinkOut - more resources

• Full Text Sources

  • Nature Publishing Group

• Other Literature Sources

  • The Lens - Patent Citations

• Miscellaneous

  • NCI CPTAC Assay Portal