Response to Falush: a role for cis-element polymorphisms in HD - PubMed (original) (raw)

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Response to Falush: a role for cis-element polymorphisms in HD

Simon C Warby et al. Am J Hum Genet. 2009 Dec.

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• Haplotype background, repeat length evolution, and Huntington's disease.
  Falush D. Falush D. Am J Hum Genet. 2009 Dec;85(6):939-42. doi: 10.1016/j.ajhg.2009.11.002. Am J Hum Genet. 2009. PMID: 20004772 Free PMC article. No abstract available.

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References

1. 1. Warby S.C., Montpetit A., Hayden A.R., Carroll J.B., Butland S.L., Visscher H., Collins J.A., Semaka A., Hudson T.J., Hayden M.R. CAG expansion in the Huntington disease gene is associated with a specific and targetable predisposing haplogroup. Am. J. Hum. Genet. 2009;84:351–366. - PMC - PubMed
2. 1. Leeflang E.P., Tavaré S., Marjoram P., Neal C.O., Srinidhi J., MacFarlane H., MacDonald M.E., Gusella J.F., de Young M., Wexler N.S., Arnheim N. Analysis of germline mutation spectra at the Huntington's disease locus supports a mitotic mutation mechanism. Hum. Mol. Genet. 1999;8:173–183. - PubMed
3. 1. Pollard L.M., Sharma R., Gómez M., Shah S., Delatycki M.B., Pianese L., Monticelli A., Keats B.J., Bidichandani S.I. Replication-mediated instability of the GAA triplet repeat mutation in Friedreich ataxia. Nucleic Acids Res. 2004;32:5962–5971. - PMC - PubMed
4. 1. Cleary J.D., Nichol K., Wang Y.H., Pearson C.E. Evidence of cis-acting factors in replication-mediated trinucleotide repeat instability in primate cells. Nat. Genet. 2002;31:37–46. - PubMed
5. 1. Langbehn D.R., Hayden M.R., Paulsen J.S., and the PREDICT-HD Investigators of the Huntington Study Group CAG-repeat length and the age of onset in Huntington disease (HD): A review and validation study of statistical approaches. Am. J. Med. Genet. B. Neuropsychiatr. Genet. 2009 Published online June 22, 2009. - PMC - PubMed

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