From meiosis to postmeiotic events: the secrets of histone disappearance - PubMed (original) (raw)

Review

. 2010 Feb;277(3):599-604.

doi: 10.1111/j.1742-4658.2009.07504.x. Epub 2009 Dec 15.

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From meiosis to postmeiotic events: the secrets of histone disappearance

Jonathan Gaucher et al. FEBS J. 2010 Feb.

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Abstract

One of the most obscure phenomena in modern biology is the near genome-wide displacement of histones that occurs during the postmeiotic phases of spermatogenesis in many species. Here we review the literature to show that, during spermatogenic differentiation, three major molecular mechanisms come together to 'prepare' the nucleosomes for facilitated disassembly and histone removal.

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