STING-ing the antiviral pathway - PubMed (original) (raw)

doi: 10.1093/jmcb/mjp048. Epub 2009 Dec 18.

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• PMID: 20022884
• DOI: 10.1093/jmcb/mjp048

STING-ing the antiviral pathway

Peyman Nakhaei et al. J Mol Cell Biol. 2010 Jun.

Abstract

The cytosolic DNA sensing pathway has remained poorly defined thus far. A recent study by Ishikawa et al. demonstrates that STING is essential for DNA-mediated type I IFN production and host defence against DNA pathogens.

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