Burn wound healing property of Cocos nucifera: An appraisal - PubMed (original) (raw)
Burn wound healing property of Cocos nucifera: An appraisal
Pallavi Srivastava et al. Indian J Pharmacol. 2008 Aug.
Abstract
Objectives: The study was undertaken to evaluate the burn wound healing property of oil of Cocos nucifera and to compare the effect of the combination of oil of Cocos nucifera and silver sulphadiazine with silver sulphadiazine alone.
Materials and methods: Partial thickness burn wounds were inflicted upon four groups of six rats each. Group I was assigned as control, Group II received the standard silver sulphadiazine. Group III was given pure oil of Cocos nucifera , and Group IV received the combination of the oil and the standard. The parameters observed were epithelialization period and percentage of wound contraction.
Results: It was noted that there was significant improvement in burn wound contraction in the group treated with the combination of Cocos nucifera and silver sulphadiazine. The period of epithelialization also decreased significantly in groups III and IV.
Conclusion: It is concluded that oil of Cocos nucifera is an effective burn wound healing agent.
Keywords: Cocos nucifera; epithelialization; silver sulphadiazine; wound contraction.
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References
- Bingham HG, Hudson D, Popp J. A retrospective review of the burn intensive care admissions for a year. J Burn Care Rehabil. 1995;16:56–8. - PubMed
- McGill V, Kowal-Vern A, Fisher SG, Kahn S, Gamelli RL. The impact of substance use on mortality and morbidity from thermal injury. J Trauma. 1995;38:931–4. - PubMed
- Bowden ML, Thompson PD, Prasad JK. Factors influencing return to employment after a burn injury. Arch Phys Med Rehabil. 1989;70:772. - PubMed
- Blanks T, Brown S, Cosgrave B, Woody J, Bentley V, O' Sullivan N, Graydon N. The Body shop Book of Wellbeing mind, body, and soul. London: Ebury Press; 1998. pp. 173–92.
- USDA Nutrient Database for Standard Reference. Release 11 September 1996.
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