The repair of DNA damages induced in normal human skin fibroblasts exposed to simulated sunlight - PubMed (original) (raw)

. 1991 Jun;126(3):338-42.

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The repair of DNA damages induced in normal human skin fibroblasts exposed to simulated sunlight

B S Rosenstein et al. Radiat Res. 1991 Jun.

Abstract

The induction and repair of DNA damages produced by exposure of normal human skin fibroblasts to the simulated sunlight produced by a solar simulator were examined. The photoproducts measured were pyrimidine dimers, E. coli endonuclease III-sensitive sites, 6-4 photoproducts, Dewar isomers, DNA-protein crosslinks, and DNA single-strand breaks. The results of these experiments serve to form a basis for the quantitation of damages induced by exposure to sunlight.

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