Transient receptor potential ankyrin 1 (TRPA1) channel as emerging target for novel analgesics and anti-inflammatory agents - PubMed (original) (raw)
Review
. 2010 Jul 22;53(14):5085-107.
doi: 10.1021/jm100062h.
Affiliations
- PMID: 20356305
- DOI: 10.1021/jm100062h
Review
Transient receptor potential ankyrin 1 (TRPA1) channel as emerging target for novel analgesics and anti-inflammatory agents
Pier Giovanni Baraldi et al. J Med Chem. 2010.
No abstract available
Similar articles
- A new tr(i)p to sense pain: TRPA1 channel as a target for novel analgesics.
Cai X. Cai X. Expert Rev Neurother. 2008 Nov;8(11):1675-81. doi: 10.1586/14737175.8.11.1675. Expert Rev Neurother. 2008. PMID: 18986238 Review. - Kv7 (KCNQ) channel modulators and neuropathic pain.
Munro G, Dalby-Brown W. Munro G, et al. J Med Chem. 2007 May 31;50(11):2576-82. doi: 10.1021/jm060989l. Epub 2007 May 10. J Med Chem. 2007. PMID: 17489574 Review. No abstract available. - Transient receptor potential channels as novel drug targets in respiratory diseases.
Nassini R, Materazzi S, De Siena G, De Cesaris F, Geppetti P. Nassini R, et al. Curr Opin Investig Drugs. 2010 May;11(5):535-42. Curr Opin Investig Drugs. 2010. PMID: 20419599 Review. - 7-Substituted-pyrrolo[3,2-d]pyrimidine-2,4-dione derivatives as antagonists of the transient receptor potential ankyrin 1 (TRPA1) channel: a promising approach for treating pain and inflammation.
Baraldi PG, Romagnoli R, Saponaro G, Aghazadeh Tabrizi M, Baraldi S, Pedretti P, Fusi C, Nassini R, Materazzi S, Geppetti P, Preti D. Baraldi PG, et al. Bioorg Med Chem. 2012 Mar 1;20(5):1690-8. doi: 10.1016/j.bmc.2012.01.020. Epub 2012 Jan 24. Bioorg Med Chem. 2012. PMID: 22325155 - TRPA1 antagonists as potential analgesic drugs.
Andrade EL, Meotti FC, Calixto JB. Andrade EL, et al. Pharmacol Ther. 2012 Feb;133(2):189-204. doi: 10.1016/j.pharmthera.2011.10.008. Epub 2011 Nov 15. Pharmacol Ther. 2012. PMID: 22119554 Review.
Cited by
- Proof-of-Concept for the Analgesic Effect and Thermoregulatory Safety of Orally Administered Multi-Target Compound SZV 1287 in Mice: A Novel Drug Candidate for Neuropathic Pain.
Horváth ÁI, Szentes N, Tékus V, Payrits M, Szőke É, Oláh E, Garami A, Fliszár-Nyúl E, Poór M, Sár C, Kálai T, Pál S, Percze K, Scholz ÉN, Mészáros T, Tóth B, Mátyus P, Helyes Z. Horváth ÁI, et al. Biomedicines. 2021 Jun 29;9(7):749. doi: 10.3390/biomedicines9070749. Biomedicines. 2021. PMID: 34209525 Free PMC article. - New strategies to develop novel pain therapies: addressing thermoreceptors from different points of view.
Fernández-Carvajal A, Fernández-Ballester G, Devesa I, González-Ros JM, Ferrer-Montiel A. Fernández-Carvajal A, et al. Pharmaceuticals (Basel). 2011 Dec 27;5(1):16-48. doi: 10.3390/ph5010016. Pharmaceuticals (Basel). 2011. PMID: 24288041 Free PMC article. - A Novel Discovery: Holistic Efficacy at the Special Organ Level of Pungent Flavored Compounds from Pungent Traditional Chinese Medicine.
Chen Z, Cao Y, Zhang Y, Qiao Y. Chen Z, et al. Int J Mol Sci. 2019 Feb 11;20(3):752. doi: 10.3390/ijms20030752. Int J Mol Sci. 2019. PMID: 30754631 Free PMC article. - The blockade of transient receptor potential ankirin 1 (TRPA1) signalling mediates antidepressant- and anxiolytic-like actions in mice.
de Moura JC, Noroes MM, Rachetti Vde P, Soares BL, Preti D, Nassini R, Materazzi S, Marone IM, Minocci D, Geppetti P, Gavioli EC, André E. de Moura JC, et al. Br J Pharmacol. 2014 Sep;171(18):4289-99. doi: 10.1111/bph.12786. Br J Pharmacol. 2014. PMID: 24846744 Free PMC article. - Deciphering Subtype-Selective Modulations in TRPA1 Biosensor Channels.
Kozai D, Sakaguchi R, Ohwada T, Mori Y. Kozai D, et al. Curr Neuropharmacol. 2015;13(2):266-78. doi: 10.2174/1570159x1302150525122020. Curr Neuropharmacol. 2015. PMID: 26411770 Free PMC article. Review.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources
Chemical Information
Molecular Biology Databases