Achieving effective pain relief in patients with chronic kidney disease: a review of analgesics in renal failure - PubMed (original) (raw)
Review
. 2011 Jan-Feb;24(1):35-40.
doi: 10.5301/jn.2010.1330.
Affiliations
- PMID: 20383865
- DOI: 10.5301/jn.2010.1330
Review
Achieving effective pain relief in patients with chronic kidney disease: a review of analgesics in renal failure
Shobhana Nayak-Rao. J Nephrol. 2011 Jan-Feb.
Abstract
Increasing evidence in literature shows that chronic pain is a common and disabling symptom in patients with chronic kidney disease (CKD). As the dialysis population all over the world ages and experiences multiple co-morbidities, nephrologists are increasingly faced with the complex task of addressing them effectively to sustain a reasonable health-related quality of life for their patients. The overall symptom burden of these patients is high and is similar to the end-of life cancer population. The complex pharmacokinetics of opioid analgesics in patients with pre-existing renal disease as well as physician unfamiliarity with the use of these drugs is a barrier to providing effective pain relief. This review deals with approaches to the management of pain in patients with CKD.
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