Characterization of human tyrosinase ectodomain expressed in Escherichia coli - PubMed (original) (raw)

Characterization of human tyrosinase ectodomain expressed in Escherichia coli

Ji-Na Kong et al. Protein Pept Lett. 2010 Aug.

Abstract

The human tyrosinase ectodomain has been expressed in Escherichia coli as a soluble form and purified by immobilized metal affinity column chromatography. The ectodomain exhibited tyrosinase activities toward the hydroxylation and oxidation reactions. Biochemical properties of the ectodomain appeared to be distinct from those of the human tyrosinase, although common features were retained.

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