Inappropriate prescribing in the hospitalized elderly patient: defining the problem, evaluation tools, and possible solutions - PubMed (original) (raw)
Review
Inappropriate prescribing in the hospitalized elderly patient: defining the problem, evaluation tools, and possible solutions
Robert L Page 2nd et al. Clin Interv Aging. 2010.
Abstract
Potentially inappropriate medication (PIM) prescribing in older adults is quite prevalent and is associated with an increased risk for adverse drug events, morbidity, and utilization of health care resources. In the acute care setting, PIM prescribing can be even more problematic due to multiple physicians and specialists who may be prescribing for a single patient as well as difficulty with medication reconciliation at transitions and limitations imposed by hospital formularies. This article highlights critical issues surrounding PIM prescribing in the acute care setting such as risk factors, screening tools, and potential strategies to minimize this significant public health problem.
Keywords: Beers’ criteria; adverse drug events; adverse drug reactions; aged; elderly; inappropriate prescribing; screening.
Similar articles
- Potentially inappropriate prescribing in an Irish elderly population in primary care.
Ryan C, O'Mahony D, Kennedy J, Weedle P, Byrne S. Ryan C, et al. Br J Clin Pharmacol. 2009 Dec;68(6):936-47. doi: 10.1111/j.1365-2125.2009.03531.x. Br J Clin Pharmacol. 2009. PMID: 20002089 Free PMC article. - Inappropriate prescribing in the elderly: a comparison of the Beers criteria and the improved prescribing in the elderly tool (IPET) in acutely ill elderly hospitalized patients.
Barry PJ, O'Keefe N, O'Connor KA, O'Mahony D. Barry PJ, et al. J Clin Pharm Ther. 2006 Dec;31(6):617-26. doi: 10.1111/j.1365-2710.2006.00783.x. J Clin Pharm Ther. 2006. PMID: 17176367 - Prevalence of potentially inappropriate medications and risk of adverse clinical outcome in a cohort of hospitalized elderly patients: results from the REPOSI Study.
Pasina L, Djade CD, Tettamanti M, Franchi C, Salerno F, Corrao S, Marengoni A, Marcucci M, Mannucci PM, Nobili A; REPOSI Investigators. Pasina L, et al. J Clin Pharm Ther. 2014 Oct;39(5):511-5. doi: 10.1111/jcpt.12178. Epub 2014 May 21. J Clin Pharm Ther. 2014. PMID: 24845066 - Application of the STOPP/START criteria: a systematic review of the prevalence of potentially inappropriate prescribing in older adults, and evidence of clinical, humanistic and economic impact.
Hill-Taylor B, Sketris I, Hayden J, Byrne S, O'Sullivan D, Christie R. Hill-Taylor B, et al. J Clin Pharm Ther. 2013 Oct;38(5):360-72. doi: 10.1111/jcpt.12059. Epub 2013 Apr 2. J Clin Pharm Ther. 2013. PMID: 23550814 Review. - Inappropriate prescribing in the older population: need for new criteria.
O'Mahony D, Gallagher PF. O'Mahony D, et al. Age Ageing. 2008 Mar;37(2):138-41. doi: 10.1093/ageing/afm189. Age Ageing. 2008. PMID: 18349010 Review.
Cited by
- Application of STOPP/START criteria in older patients in primary care using RStudio®.
González-Munguía S, Munguía-López O, Sánchez Sánchez E. González-Munguía S, et al. BMC Geriatr. 2024 Sep 25;24(1):782. doi: 10.1186/s12877-024-05376-5. BMC Geriatr. 2024. PMID: 39322952 Free PMC article. - Potentially inappropriate prescribing among older adults with hypertension in China: prevalence and related comorbidities across different outpatient settings.
Chen J, Wang S, Lu L, Yang Y, Wang K, Zheng J, Zhou Z, Guo P, Cai Y, Zhang Q. Chen J, et al. Front Pharmacol. 2024 Aug 15;15:1439230. doi: 10.3389/fphar.2024.1439230. eCollection 2024. Front Pharmacol. 2024. PMID: 39211782 Free PMC article. - Strategies to Improve Emergency Transitions From Long-Term Care Facilities: A Scoping Review.
Tate K, Cummings G, Jacobsen F, Halas G, Van den Bergh G, Devkota R, Shrestha S, Doupe M. Tate K, et al. Gerontologist. 2024 Jul 1;64(7):gnae036. doi: 10.1093/geront/gnae036. Gerontologist. 2024. PMID: 38661440 Free PMC article. Review. - Clinical decision support system supported interventions in hospitalized older patients: a matter of natural course and adequate timing.
Zwietering NA, Linkens A, Kurstjens D, van der Kuy P, van Nie-Visser N, van de Loo B, Hurkens K, Spaetgens B. Zwietering NA, et al. BMC Geriatr. 2024 Mar 14;24(1):256. doi: 10.1186/s12877-024-04823-7. BMC Geriatr. 2024. PMID: 38486200 Free PMC article. - Exploring the Roles of Nurses in Medication Reconciliation for Older Adults at Hospital Discharge: A Narrative Approach.
Zhu LL, Wang YH, Lan MJ, Zhou Q. Zhu LL, et al. Clin Interv Aging. 2024 Mar 5;19:367-373. doi: 10.2147/CIA.S450319. eCollection 2024. Clin Interv Aging. 2024. PMID: 38476831 Free PMC article.
References
- Institute of Medicine . To Err Is Human: Building A Safer Health System. Washington, DC: National Academies Press; 1999. - PubMed
- Gallagher P, Barry P, O’Mahony D. Inappropriate prescribing in the elderly. J Clin Pharm Ther. 2007;32(2):113–121. - PubMed
- Spinewine A, Schmader KE, Barber N, et al. Appropriate prescribing in elderly people: how well can it be measured and optimised? Lancet. 2007;370(9582):173–184. - PubMed
Publication types
MeSH terms
LinkOut - more resources
Full Text Sources