Human herpesvirus 6-A, 6-B, and 7 in vitreous fluid samples - PubMed (original) (raw)
Human herpesvirus 6-A, 6-B, and 7 in vitreous fluid samples
Jeffrey I Cohen et al. J Med Virol. 2010 May.
Abstract
Human herpesvirus 6 and 7 (HHV-6, HHV-7) have been associated with several neurologic syndromes and have been detected in nervous tissue from healthy persons; however, only two cases of HHV-6A have been reported to be associated with intraocular inflammatory disease. Vitreous fluid was tested from 101 patients, including 69 samples from patients with ocular inflammation including CMV retinitis, idiopathic retinitis, iritis, and vitritis, for HHV-6A, HHV-6B, and HHV-7 DNA by PCR. HHV-6A DNA (4,950 copies per ml) was detected in vitreous fluid from one patient with CMV retinitis, HHV-6B DNA (10,140 copies per ml) was detected in vitreous fluid from one patient with idiopathic ocular inflammation in the absence of CMV DNA, and HHV-7 was not detected in any of the vitreous samples. HHV-6A, HHV-6B, and HHV-7 DNA are detectable in less than 2% of vitreous samples in patients with ocular inflammation.
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References
- Chan PK, Ng HK, Cheung JL, Ng KC, Cheng AF. Prevalence and distribution of human herpesvirus 7 in normal brain. J Med Virol. 2000;62:345–8. - PubMed
- Chan PK, Ng HK, Hui M, Cheng AF. Prevalence and distribution of human herpesvirus 6 variants A and B in adult human brain. J Med Virol. 2001;64:42–6. - PubMed
- Cohen JI. Human herpesvirus types 6 and 7. In: Mandell G, Bennett J, Dolin R, editors. Principles and Practice of Infectious Diseases. Philadelphia: Elsevier, Churchill Livingstone; 2010. pp. 2011–2015.
- Cuomo L, Trivedi P, Cardillo MR, Gagliardi FM, Vecchione A, Caruso R, Calogero A, Frati L, Faggioni A, Ragona G. Human herpesvirus 6 infection in neoplastic and normal brain tissue. J Med Virol. 2001;63:45–51. - PubMed