Demographic consequences of defeating aging - PubMed (original) (raw)
Demographic consequences of defeating aging
Leonid A Gavrilov et al. Rejuvenation Res. 2010 Apr-Jun.
Abstract
A common objection against starting a large-scale biomedical war on aging is the fear of catastrophic population consequences (overpopulation). This fear is only exacerbated by the fact that no detailed demographic projections for radical life extension scenario have been conducted so far. This study explores different demographic scenarios and population projections, in order to clarify what could be the demographic consequences of a successful biomedical war on aging. A general conclusion of this study is that population changes are surprisingly slow in their response to a dramatic life extension. For example, we applied the cohort-component method of population projections to 2005 Swedish population for several scenarios of life extension and a fertility schedule observed in 2005. Even for very long 100-year projection horizon, with the most radical life extension scenario (assuming no aging at all after age 60), the total population increases by 22% only (from 9.1 to 11.0 million). Moreover, if some members of society reject to use new anti-aging technologies for some religious or any other reasons (inconvenience, non-compliance, fear of side effects, costs, etc.), then the total population size may even decrease over time. Thus, even in the case of the most radical life extension scenario, population growth could be relatively slow and may not necessarily lead to overpopulation. Therefore, the real concerns should be placed not on the threat of catastrophic population consequences (overpopulation), but rather on such potential obstacles to a success of biomedical war on aging, as scientific, organizational, and financial limitations.
Figures
FIG. 1.
Projection of the Swedish population until year 2105, assuming the negligible senescence scenario. Life extension interventions start at age 60 years, with a 30-year time delay from now.
FIG. 2.
Population pyramid of Sweden projected for year 2105, when only 10% of a population initially accepts interventions leading to negligible senescence.
FIG. 3.
Population projection for a scenario of growing acceptance of antiaging interventions. Projection of the Swedish population until year 2105, assuming the negligible senescence scenario for initially small proportion of population (10%), with growing acceptance rate over time. Life extension interventions start at age 60 years, with 30-year time delay from now.
Similar articles
- Life Extension and Overpopulation: Demography, Morals, and the Malthusian Objection.
Davoudpour S, Davis JK. Davoudpour S, et al. HEC Forum. 2022 Dec 26. doi: 10.1007/s10730-022-09504-9. Online ahead of print. HEC Forum. 2022. PMID: 36571631 - Aging in Kerala: one more population problem?
Rajan SI. Rajan SI. Asia Pac Popul J. 1989 Jun;4(2):19-48. Asia Pac Popul J. 1989. PMID: 12316022 - Alternative projections of mortality and disability by cause 1990-2020: Global Burden of Disease Study.
Murray CJ, Lopez AD. Murray CJ, et al. Lancet. 1997 May 24;349(9064):1498-504. doi: 10.1016/S0140-6736(96)07492-2. Lancet. 1997. PMID: 9167458 - Aging in America in the twenty-first century: demographic forecasts from the MacArthur Foundation Research Network on an Aging Society.
Olshansky SJ, Goldman DP, Zheng Y, Rowe JW. Olshansky SJ, et al. Milbank Q. 2009 Dec;87(4):842-62. doi: 10.1111/j.1468-0009.2009.00581.x. Milbank Q. 2009. PMID: 20021588 Free PMC article. Review. - Projections of Ambient Temperature- and Air Pollution-Related Mortality Burden Under Combined Climate Change and Population Aging Scenarios: a Review.
Chen K, Vicedo-Cabrera AM, Dubrow R. Chen K, et al. Curr Environ Health Rep. 2020 Sep;7(3):243-255. doi: 10.1007/s40572-020-00281-6. Curr Environ Health Rep. 2020. PMID: 32542573 Review.
Cited by
- STÁRNUTÍ A DLOUHOVĚKOST: ZÁKONY A PROGNÓZY ÚMRTNOSTI PRO STÁRNOUCÍ POPULACE.
Gavrilova NS, Gavrilov LA. Gavrilova NS, et al. Demografie. 2011;53(2):109-128. Demografie. 2011. PMID: 25242821 Free PMC article. Czech. - Social factors associated with centenarian rate (CR) in 32 OECD countries.
Kim JI. Kim JI. BMC Int Health Hum Rights. 2013 Mar 8;13:16. doi: 10.1186/1472-698X-13-16. BMC Int Health Hum Rights. 2013. PMID: 23497053 Free PMC article. - The demographic and biomedical case for late-life interventions in aging.
Rae MJ, Butler RN, Campisi J, de Grey AD, Finch CE, Gough M, Martin GM, Vijg J, Perrott KM, Logan BJ. Rae MJ, et al. Sci Transl Med. 2010 Jul 14;2(40):40cm21. doi: 10.1126/scitranslmed.3000822. Sci Transl Med. 2010. PMID: 20630854 Free PMC article. - Interview with Leonid A. Gavrilov, Ph.D.and Natalia Gavrilova, Ph.D.
Gavrilov LA, Gavrilova N. Gavrilov LA, et al. Rejuvenation Res. 2009 Oct;12(5):371-4. doi: 10.1089/rej.2009.0979. Rejuvenation Res. 2009. PMID: 19929260 Free PMC article. No abstract available.
References
- O'Neil BC. Balk D. Brickman M. Ezra M. A guide to global population projections. Demographic Res. 2001;4:203–288.
- Preston SH. Heuveline P. Guillot M. Demography. Measuring and Modeling Population Processes. Blackwell; Oxford: 2001.
Publication types
MeSH terms
LinkOut - more resources
Full Text Sources