GPCR-OKB: the G Protein Coupled Receptor Oligomer Knowledge Base - PubMed (original) (raw)

. 2010 Jul 15;26(14):1804-5.

doi: 10.1093/bioinformatics/btq264. Epub 2010 May 25.

Kevin Dorff, Jufang Shan, Marta Camacho-Artacho, Lucy Skrabanek, Bas Vroling, Michel Bouvier, Lakshmi A Devi, Susan R George, Jonathan A Javitch, Martin J Lohse, Graeme Milligan, Richard R Neubig, Krzysztof Palczewski, Marc Parmentier, Jean-Philippe Pin, Gerrit Vriend, Fabien Campagne, Marta Filizola

Affiliations

• PMID: 20501551
• PMCID: PMC2894509
• DOI: 10.1093/bioinformatics/btq264

GPCR-OKB: the G Protein Coupled Receptor Oligomer Knowledge Base

George Khelashvili et al. Bioinformatics. 2010.

Abstract

Summary: Rapid expansion of available data about G Protein Coupled Receptor (GPCR) dimers/oligomers over the past few years requires an effective system to organize this information electronically. Based on an ontology derived from a community dialog involving colleagues using experimental and computational methodologies, we developed the GPCR-Oligomerization Knowledge Base (GPCR-OKB). GPCR-OKB is a system that supports browsing and searching for GPCR oligomer data. Such data were manually derived from the literature. While focused on GPCR oligomers, GPCR-OKB is seamlessly connected to GPCRDB, facilitating the correlation of information about GPCR protomers and oligomers.

Availability and implementation: The GPCR-OKB web application is freely available at http://www.gpcr-okb.org

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