When fibroblasts MET iPSCs - PubMed (original) (raw)
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doi: 10.1016/j.stem.2010.05.018. Epub 2010 Jun 17.
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- PMID: 20621040
- DOI: 10.1016/j.stem.2010.05.018
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When fibroblasts MET iPSCs
Jose M Polo et al. Cell Stem Cell. 2010.
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Abstract
Two independent studies by Li et al. (2010) and Samavarchi-Tehrani et al. (2010) in this issue of Cell Stem Cell suggest that a mesenchymal-to-epithelial transition is a critical initiating event during the derivation of induced pluripotent stem cells (iPSCs) from fibroblasts, indicating remarkable similarities between cellular reprogramming, development, and cancer.
Copyright (c) 2010 Elsevier Inc. All rights reserved.
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- A mesenchymal-to-epithelial transition initiates and is required for the nuclear reprogramming of mouse fibroblasts.
Li R, Liang J, Ni S, Zhou T, Qing X, Li H, He W, Chen J, Li F, Zhuang Q, Qin B, Xu J, Li W, Yang J, Gan Y, Qin D, Feng S, Song H, Yang D, Zhang B, Zeng L, Lai L, Esteban MA, Pei D. Li R, et al. Cell Stem Cell. 2010 Jul 2;7(1):51-63. doi: 10.1016/j.stem.2010.04.014. Epub 2010 Jun 17. Cell Stem Cell. 2010. PMID: 20621050 - Functional genomics reveals a BMP-driven mesenchymal-to-epithelial transition in the initiation of somatic cell reprogramming.
Samavarchi-Tehrani P, Golipour A, David L, Sung HK, Beyer TA, Datti A, Woltjen K, Nagy A, Wrana JL. Samavarchi-Tehrani P, et al. Cell Stem Cell. 2010 Jul 2;7(1):64-77. doi: 10.1016/j.stem.2010.04.015. Epub 2010 Jun 17. Cell Stem Cell. 2010. PMID: 20621051
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