Childhood acute leukemia, early common infections, and allergy: The ESCALE Study - PubMed (original) (raw)
. 2010 Nov 1;172(9):1015-27.
doi: 10.1093/aje/kwq233. Epub 2010 Aug 31.
Laurent Orsi, Florence Menegaux, Arnaud Petit, André Baruchel, Yves Bertrand, Anne Lambilliotte, Alain Robert, Gérard Michel, Geneviève Margueritte, Julie Tandonnet, Françoise Mechinaud, Pierre Bordigoni, Denis Hémon, Jacqueline Clavel
Affiliations
- PMID: 20807738
- DOI: 10.1093/aje/kwq233
Childhood acute leukemia, early common infections, and allergy: The ESCALE Study
Jérémie Rudant et al. Am J Epidemiol. 2010.
Abstract
This study investigated the role of factors considered related to early stimulation of the immune system in the etiology of childhood acute leukemia. The national registry-based case-control study ESCALE was carried out in France in 2003-2004. Population controls were frequency matched to cases on age and gender. Data were obtained from structured telephone questionnaires administered to mothers. Odds ratios were estimated using unconditional regression models adjusted for potential confounders. Included were 634 acute lymphoblastic leukemia cases, 86 acute myeloblastic leukemia cases, and 1,494 controls aged ≥1 year. Negative associations were observed between acute lymphoblastic leukemia and birth order (P for trend < 0.0001), attendance at a day-care center before age 1 year (odds ratio (OR) = 0.8, 95% confidence interval (CI): 0.6, 1.1), prolonged breastfeeding (OR = 0.7, 95% CI: 0.5, 1.0), repeated early common infections (OR = 0.7, 95% CI: 0.6, 0.9), regular contact with farm animals (OR = 0.6, 95% CI: 0.5, 0.8), frequent farm visits in early life (OR = 0.4, 95% CI: 0.3, 0.6), and history of asthma (OR = 0.7, 95% CI: 0.4, 1.0) or eczema (OR = 0.7, 95% CI: 0.6, 0.9). Results support the hypothesis that repeated early infections and asthma may play a role against childhood acute leukemia.
Similar articles
- Childhood hematopoietic malignancies and parental use of tobacco and alcohol: the ESCALE study (SFCE).
Rudant J, Menegaux F, Leverger G, Baruchel A, Lambilliotte A, Bertrand Y, Patte C, Pacquement H, Vérité C, Robert A, Michel G, Margueritte G, Gandemer V, Hémon D, Clavel J. Rudant J, et al. Cancer Causes Control. 2008 Dec;19(10):1277-90. doi: 10.1007/s10552-008-9199-5. Epub 2008 Jul 10. Cancer Causes Control. 2008. PMID: 18618277 - Risk of childhood leukemia associated with vaccination, infection, and medication use in childhood: the Cross-Canada Childhood Leukemia Study.
MacArthur AC, McBride ML, Spinelli JJ, Tamaro S, Gallagher RP, Theriault GP. MacArthur AC, et al. Am J Epidemiol. 2008 Mar 1;167(5):598-606. doi: 10.1093/aje/kwm339. Epub 2007 Dec 12. Am J Epidemiol. 2008. PMID: 18079130 - Family history of autoimmune thyroid disease and childhood acute leukemia.
Perillat-Menegaux F, Clavel J, Auclerc MF, Baruchel A, Leverger G, Nelken B, Philippe N, Sommelet D, Vilmer E, Hémon D. Perillat-Menegaux F, et al. Cancer Epidemiol Biomarkers Prev. 2003 Jan;12(1):60-3. Cancer Epidemiol Biomarkers Prev. 2003. PMID: 12540505 - The association between atopy and childhood/adolescent leukemia: a meta-analysis.
Linabery AM, Jurek AM, Duval S, Ross JA. Linabery AM, et al. Am J Epidemiol. 2010 Apr 1;171(7):749-64. doi: 10.1093/aje/kwq004. Epub 2010 Mar 12. Am J Epidemiol. 2010. PMID: 20228139 Free PMC article. Review. - Etiology of common childhood acute lymphoblastic leukemia: the adrenal hypothesis.
Schmiegelow K, Vestergaard T, Nielsen SM, Hjalgrim H. Schmiegelow K, et al. Leukemia. 2008 Dec;22(12):2137-41. doi: 10.1038/leu.2008.212. Epub 2008 Aug 21. Leukemia. 2008. PMID: 18719616 Review.
Cited by
- Early-life infection depletes preleukemic cells in a mouse model of hyperdiploid B-cell acute lymphoblastic leukemia.
Farrokhi A, Atre T, Salitra S, Aletaha M, Márquez AC, Gynn M, Fidanza M, Jo S, Rolf N, Simmons K, Duque-Afonso J, Cleary ML, Seif AE, Kollmann T, Gantt S, Reid GSD. Farrokhi A, et al. Blood. 2024 Aug 22;144(8):809-821. doi: 10.1182/blood.2024025038. Blood. 2024. PMID: 38875504 Free PMC article. - Factors Attributed to Breastfeeding Success in a Tertiary Obstetric Hospital.
LeMoine FV, Witt C, Howard S, Chapple A, Pam L, Sutton EF. LeMoine FV, et al. Womens Health Rep (New Rochelle). 2022 Jul 7;3(1):624-632. doi: 10.1089/whr.2022.0045. eCollection 2022. Womens Health Rep (New Rochelle). 2022. PMID: 36185071 Free PMC article. - Potential Correlation Between Eczema and Hematological Malignancies Risk: A Systematic Review and Meta-Analysis.
Liang Z, Liu J, Jin H, Teng Y, Xu S, Yan W, Zhu Y. Liang Z, et al. Front Med (Lausanne). 2022 Jun 29;9:912136. doi: 10.3389/fmed.2022.912136. eCollection 2022. Front Med (Lausanne). 2022. PMID: 35847819 Free PMC article. - Creation of a nationwide breastfeeding policy for surgical residents: a scoping review protocol.
Ziolkowski N, Rogowsky L, Innis J, Grant Buechner A, Springall E, Dengler J. Ziolkowski N, et al. BMJ Open. 2022 Jun 13;12(6):e047466. doi: 10.1136/bmjopen-2020-047466. BMJ Open. 2022. PMID: 35697452 Free PMC article. - AllergoOncology: Role of immune cells and immune proteins.
Di Gioacchino M, Della Valle L, Allegra A, Pioggia G, Gangemi S. Di Gioacchino M, et al. Clin Transl Allergy. 2022 Mar;12(3):e12133. doi: 10.1002/clt2.12133. Clin Transl Allergy. 2022. PMID: 35344301 Free PMC article. Review.
Publication types
MeSH terms
LinkOut - more resources
Full Text Sources
Medical