Seroprevalence of tissue invading parasitic infections diagnosed by ELISA in Korea - PubMed (original) (raw)

Seroprevalence of tissue invading parasitic infections diagnosed by ELISA in Korea

Mi Kyung Lee et al. J Korean Med Sci. 2010 Sep.

Abstract

Seroprevalence of the IgG antibodies for Clonorchis sinensis, Paragonimus westermani, Taenia solium metacestode (cysticercus), and Spirometra erinacei plerocercoid (sparganum) was measured using enzyme-linked immunosorbent assay (ELISA) in sera of patients in Korea from 1993 to 2006. A total of 74,448 specimens referred nationwide from 121 hospitals revealed an IgG positive rate of 7.6% for the 4 parasites. The IgG positive rate (18.7%) for the 4 parasites in 1993 decreased gradually to 6.6% in 2006. Individual positive rate decreased from 5.2% (1993) to 1.6% (2006) for C. sinensis, from 2.8% (1993) to 1.1% (2006) for P. westermani, from 8.3% (1993) to 2.2% (2006) for cysticercus, and from 2.6% (1993) to 1.6% (2006) for sparganum. The positive rate was highest (21.2%) in the group of patients who ranged in age from 50-59 yr old, and in the group that was referred from the Seoul area (55.9%). In conclusion, our results suggest that tissue invading parasitic infections should always be included in differential diagnosis for patients with eosinophilia associated lesions of the central nervous system, liver, and lungs in Korea.

Keywords: Clonorchis sinensis; Enzyme-Linked Immunosorbent Assay; Paragonimus westermani; Seroepidemiologic Studies; Spirometra erinacei Plerocercoid; Taenia solium metacestode; Tissue Invading Parasitic Infections.

PubMed Disclaimer

Figures

Fig. 1

Fig. 1

Seropositive rates of the 4 parasitic infections by age groups. (A) 30-39 yr-old, (B) 40-49 yr-old, (C) 50-59 yr-old, and (D) 60-69 yr-old groups. The antibody positive rate of clonorchiasis was higher than that of cysticercosis in patients in their thirties and forties (A, B), but this pattern was reversed in patients in their fifties and sixties (C, D).

Fig. 2

Fig. 2

Seropositive rates of parasitic infections according to the referred areas. (A) Total positive rate, (B) cysticercosis, and (C) sparganosis.

References

    1. Seo BS, Rim HJ, Loh SH, Cho SY, Park SC, Bae JW, Kim JH, Lee JS, Koo BY, Kim KS. Study on the status of helminthic infections in Koreans. Korean J Parasitol. 1969;7:53–70. - PubMed
    1. Kim CH, Park CH, Kim HJ, Chun HB, Min HK, Koh TY, Soh CT. Prevalence of intestinal parasites in Korea. Korean J Parasitol. 1971;9:25–38. - PubMed
    1. Hong ST, Chai JY, Choi MH, Huh S, Rim HJ, Lee SH. A successful experience of soil-transmitted helminth control in the Republic of Korea. Korean J Parasitol. 2006;44:177–185. - PMC - PubMed
    1. Cho SH, Lee KY, Lee BC, Cho PY, Cheun HI, Hong ST, Sohn WM, Kim TS. Prevalence of clonorchiasis in southern endemic areas of Korea in 2006. Korean J Parasitol. 2008;46:133–137. - PMC - PubMed
    1. Shim YS, Cho SY, Han YC. Pulmonary paragonimiasis: a Korean perspectives. Sem Resp Med. 1991;12:35–45.

Publication types

MeSH terms

Substances

LinkOut - more resources