A cellular view of Nf2 in liver homeostasis and tumorigenesis - PubMed (original) (raw)
Comment
. 2010 Sep 14;19(3):363-4.
doi: 10.1016/j.devcel.2010.08.015.
Affiliations
- PMID: 20833359
- DOI: 10.1016/j.devcel.2010.08.015
Free article
Comment
A cellular view of Nf2 in liver homeostasis and tumorigenesis
Kai Breuhahn et al. Dev Cell. 2010.
Free article
Abstract
How liver adjusts and stabilizes its size is unsolved so far; the answers to this question may also provide insights into mechanisms of hepatocarcinogenesis. Two recent papers suggest a role for Merlin/Nf2 in control of liver cell turnover, but results appear conflicting at first glance.
Copyright © 2010 Elsevier Inc. All rights reserved.
Comment on
- The Merlin/NF2 tumor suppressor functions through the YAP oncoprotein to regulate tissue homeostasis in mammals.
Zhang N, Bai H, David KK, Dong J, Zheng Y, Cai J, Giovannini M, Liu P, Anders RA, Pan D. Zhang N, et al. Dev Cell. 2010 Jul 20;19(1):27-38. doi: 10.1016/j.devcel.2010.06.015. Dev Cell. 2010. PMID: 20643348 Free PMC article. - Nf2/Merlin controls progenitor homeostasis and tumorigenesis in the liver.
Benhamouche S, Curto M, Saotome I, Gladden AB, Liu CH, Giovannini M, McClatchey AI. Benhamouche S, et al. Genes Dev. 2010 Aug 15;24(16):1718-30. doi: 10.1101/gad.1938710. Epub 2010 Jul 30. Genes Dev. 2010. PMID: 20675406 Free PMC article.
Publication types
LinkOut - more resources
Full Text Sources
Miscellaneous