Plant and animal sensors of conserved microbial signatures - PubMed (original) (raw)
Review
. 2010 Nov 19;330(6007):1061-4.
doi: 10.1126/science.1189468.
Affiliations
- PMID: 21097929
- DOI: 10.1126/science.1189468
Review
Plant and animal sensors of conserved microbial signatures
Pamela C Ronald et al. Science. 2010.
Erratum in
- Erratum for the Review "Plant and animal sensors of conserved microbial signatures" by P. C. Ronald and B. Beutler.
[No authors listed] [No authors listed] Science. 2015 Sep 11;349(6253):aad3218. doi: 10.1126/science.aad3218. Science. 2015. PMID: 26359405 No abstract available.
Abstract
The last common ancestor of plants and animals may have lived 1 billion years ago. Plants and animals have occasionally exchanged genes but, for the most part, have countered selective pressures independently. Microbes (bacteria, eukaryotes, and viruses) were omnipresent threats, influencing the direction of multicellular evolution. Receptors that detect molecular signatures of infectious organisms mediate awareness of nonself and are integral to host defense in plants and animals alike. The discoveries leading to elucidation of these receptors and their ligands followed a similar logical and methodological pathway in both plant and animal research.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources