Eccrine porocarcinoma of the vulva: a case report and review of literature - PubMed (original) (raw)
Review
Eccrine porocarcinoma of the vulva: a case report and review of literature
Patrick A Adegboyega. Int J Gynecol Pathol. 2011 Jan.
Abstract
A case of a 48-year-old woman with a 5 cm left vulvar mass that grew over a six month period is presented. Histopathologic examination of the excised mass was diagnostic of malignant eccrine poroma (eccrine porocarcinoma) with in-situ component. Due to the rarity of this tumor (only five vulvar cases previously reported) and its heterogeneous non-specific clinical and histologic features, the tumor often presents as a diagnostic challenge to clinicians and pathologists. The tumor may be mistaken for a metastasis in cases where the tumor cells are poorly differentiated or for a squamous cell carcinoma in cases with extensive squamous differentiation. There is a need for correct diagnosis of this rare entity - so that appropriate therapy can be instituted in a timely manner. The pertinent literature is reviewed highlighting the diagnostic histomorphologic features and the immunohistochemical profile for making the correct diagnosis of eccrine porocarcinoma.
Similar articles
- Eccrine porocarcinoma of the vulva: a case report and review of the literature.
Fujimine-Sato A, Toyoshima M, Shigeta S, Toki A, Kuno T, Sato I, Watanabe M, Niikura H, Yaegashi N. Fujimine-Sato A, et al. J Med Case Rep. 2016 Nov 10;10(1):319. doi: 10.1186/s13256-016-1106-1. J Med Case Rep. 2016. PMID: 27832810 Free PMC article. Review. - Primary eccrine porocarcinoma of the finger with transit forearm and axillary metastasis.
Bhat W, Akhtar S, Khotwal A, Platt AJ. Bhat W, et al. Ann Plast Surg. 2011 Apr;66(4):344-6. doi: 10.1097/SAP.0b013e3181e35c8d. Ann Plast Surg. 2011. PMID: 21042176 - [Eccrine porocarcinoma of the scalp].
Ekmekcı S, Lebe B. Ekmekcı S, et al. Turk Patoloji Derg. 2013;29(2):156-9. doi: 10.5146/tjpath.2013.01169. Turk Patoloji Derg. 2013. PMID: 23661356 Turkish. - Eccrine porocarcinoma arising within an area of Bowen disease.
Lowney AC, Mc Aleer MA, O'Connor K, Fitzgibbon JF, Bourke JF. Lowney AC, et al. Clin Exp Dermatol. 2012 Mar;37(2):136-8. doi: 10.1111/j.1365-2230.2011.04167.x. Epub 2011 Oct 5. Clin Exp Dermatol. 2012. PMID: 21973218 - Eccrine porocarcinoma: a report of 2 cases and review of the literature.
Nguyen A, Nguyen AV. Nguyen A, et al. Cutis. 2014 Jan;93(1):43-6. Cutis. 2014. PMID: 24505584 Review.
Cited by
- Intergluteal Cleft Eccrine Porocarcinoma with Metastasis to Inguinal Region and Lung: Case Report and Review of the Literature.
Fernández-Ferreira R, Alvarado-Luna G, Motola-Kuba D, Mackinney-Novelo I, Cervera-Ceballos EE, Segura-Rivera R. Fernández-Ferreira R, et al. Case Rep Oncol. 2020 Dec 10;13(3):1463-1473. doi: 10.1159/000510311. eCollection 2020 Sep-Dec. Case Rep Oncol. 2020. PMID: 33442371 Free PMC article. Review. - Porocarcinoma; presentation and management, a meta-analysis of 453 cases.
Salih AM, Kakamad FH, Baba HO, Salih RQ, Hawbash MR, Mohammed SH, Othman S, Saeed YA, Habibullah IJ, Muhialdeen AS, Nawroly RO, Hammood ZD, Abdulkarim NH. Salih AM, et al. Ann Med Surg (Lond). 2017 Jun 20;20:74-79. doi: 10.1016/j.amsu.2017.06.027. eCollection 2017 Aug. Ann Med Surg (Lond). 2017. PMID: 28721214 Free PMC article. Review. - Eccrine porocarcinoma of the vulva: a case report and review of the literature.
Fujimine-Sato A, Toyoshima M, Shigeta S, Toki A, Kuno T, Sato I, Watanabe M, Niikura H, Yaegashi N. Fujimine-Sato A, et al. J Med Case Rep. 2016 Nov 10;10(1):319. doi: 10.1186/s13256-016-1106-1. J Med Case Rep. 2016. PMID: 27832810 Free PMC article. Review.