A helix-loop-helix protein related to the immunoglobulin E box-binding proteins - PubMed (original) (raw)

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A helix-loop-helix protein related to the immunoglobulin E box-binding proteins

C S Carr et al. Mol Cell Biol. 1990 Aug.

Abstract

A human cDNA encoding a novel protein in the helix-loop-helix family has been isolated by screening a bacteriophage expression library with a probe containing the binding site for major late transcription factor. The protein encoded by this cDNA, TFEB, probably recognizes E-box sequences in the heavy-chain immunoglobulin enhancer.

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