Metalloproteinases and their inhibitors in matrix remodeling - PubMed (original) (raw)

Review

Metalloproteinases and their inhibitors in matrix remodeling

L M Matrisian. Trends Genet. 1990 Apr.

Abstract

The matrix metalloproteinases are a tightly regulated family of enzymes that degrade extracellular matrix and basement membrane components. Recent evidence suggests that these proteases and their specific inhibitors play important roles in normal developmental processes and in pathological conditions. Interestingly, experiments designed to improve our understanding of metalloproteinase regulation have also resulted in new insights into mechanisms by which growth factors and proto-oncogenes may regulate biological processes.

PubMed Disclaimer

Similar articles

• Matrix metalloproteinases: a review.
  Birkedal-Hansen H, Moore WG, Bodden MK, Windsor LJ, Birkedal-Hansen B, DeCarlo A, Engler JA. Birkedal-Hansen H, et al. Crit Rev Oral Biol Med. 1993;4(2):197-250. doi: 10.1177/10454411930040020401. Crit Rev Oral Biol Med. 1993. PMID: 8435466 Review.
• Matrix degrading metalloproteinases.
  Ennis BW, Matrisian LM. Ennis BW, et al. J Neurooncol. 1994;18(2):105-9. doi: 10.1007/BF01050416. J Neurooncol. 1994. PMID: 7964973 Review.
• The matrix metalloproteinases and their natural inhibitors: prospects for treating degenerative tissue diseases.
  Docherty AJ, O'Connell J, Crabbe T, Angal S, Murphy G. Docherty AJ, et al. Trends Biotechnol. 1992 Jun;10(6):200-7. doi: 10.1016/0167-7799(92)90214-g. Trends Biotechnol. 1992. PMID: 1368394 Review.
• Structural biochemistry and activation of matrix metalloproteases.
  Kleiner DE Jr, Stetler-Stevenson WG. Kleiner DE Jr, et al. Curr Opin Cell Biol. 1993 Oct;5(5):891-7. doi: 10.1016/0955-0674(93)90040-w. Curr Opin Cell Biol. 1993. PMID: 8240832 Review.
• The matrix metalloproteinases and their inhibitors.
  Murphy G, Docherty AJ. Murphy G, et al. Am J Respir Cell Mol Biol. 1992 Aug;7(2):120-5. doi: 10.1165/ajrcmb/7.2.120. Am J Respir Cell Mol Biol. 1992. PMID: 1497900 Review.

Cited by

• Attenuation of extrinsic signaling reveals the importance of matrix remodeling on maintenance of embryonic stem cell self-renewal.
  Przybyla LM, Voldman J. Przybyla LM, et al. Proc Natl Acad Sci U S A. 2012 Jan 17;109(3):835-40. doi: 10.1073/pnas.1103100109. Epub 2012 Jan 3. Proc Natl Acad Sci U S A. 2012. PMID: 22215601 Free PMC article.
• Negative regulation of the rat stromelysin gene promoter by retinoic acid is mediated by an AP1 binding site.
  Nicholson RC, Mader S, Nagpal S, Leid M, Rochette-Egly C, Chambon P. Nicholson RC, et al. EMBO J. 1990 Dec;9(13):4443-54. doi: 10.1002/j.1460-2075.1990.tb07895.x. EMBO J. 1990. PMID: 2176152 Free PMC article.
• Interstitial collagenase gene expression in oral squamous cell carcinoma.
  Gray ST, Wilkins RJ, Yun K. Gray ST, et al. Am J Pathol. 1992 Aug;141(2):301-6. Am J Pathol. 1992. PMID: 1323216 Free PMC article.
• MMP-9 secretion and MMP-2 activation distinguish invasive and metastatic sublines of a mouse mammary carcinoma system showing epithelial-mesenchymal transition traits.
  Tester AM, Ruangpanit N, Anderson RL, Thompson EW. Tester AM, et al. Clin Exp Metastasis. 2000;18(7):553-60. doi: 10.1023/a:1011953118186. Clin Exp Metastasis. 2000. PMID: 11688960
• Temporal and spatial expression of tissue inhibitors of metalloproteinases 1 and 2 (TIMP-1 and -2) in the bovine corpus luteum.
  Zhang B, Moses MA, Tsang PC. Zhang B, et al. Reprod Biol Endocrinol. 2003 Nov 7;1:85. doi: 10.1186/1477-7827-1-85. Reprod Biol Endocrinol. 2003. PMID: 14613539 Free PMC article.

Publication types

MeSH terms

Substances

LinkOut - more resources

• Full Text Sources

  • Elsevier Science

• Other Literature Sources

  • The Lens - Patent Citations Database