Impact of high-throughput screening in biomedical research - PubMed (original) (raw)
Review
doi: 10.1038/nrd3368.
Martyn N Banks, Dejan Bojanic, David J Burns, Dragan A Cirovic, Tina Garyantes, Darren V S Green, Robert P Hertzberg, William P Janzen, Jeff W Paslay, Ulrich Schopfer, G Sitta Sittampalam
Affiliations
- PMID: 21358738
- DOI: 10.1038/nrd3368
Review
Impact of high-throughput screening in biomedical research
Ricardo Macarron et al. Nat Rev Drug Discov. 2011 Mar.
Abstract
High-throughput screening (HTS) has been postulated in several quarters to be a contributory factor to the decline in productivity in the pharmaceutical industry. Moreover, it has been blamed for stifling the creativity that drug discovery demands. In this article, we aim to dispel these myths and present the case for the use of HTS as part of a proven scientific tool kit, the wider use of which is essential for the discovery of new chemotypes.
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