Linking calorie restriction to longevity through sirtuins and autophagy: any role for TOR - PubMed (original) (raw)
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Linking calorie restriction to longevity through sirtuins and autophagy: any role for TOR
M V Blagosklonny. Cell Death Dis. 2010.
No abstract available
Figures
Figure 1
Linking CR, sirtuins, autophagy network to prolong lifespan. (a) CR and resveratrol activate autophagy through sirtuins, thus extending lifespan (see Morselli et al., this issue). (b) Integrating panel a with the TOR pathway
Comment on
- Caloric restriction and resveratrol promote longevity through the Sirtuin-1-dependent induction of autophagy.
Morselli E, Maiuri MC, Markaki M, Megalou E, Pasparaki A, Palikaras K, Criollo A, Galluzzi L, Malik SA, Vitale I, Michaud M, Madeo F, Tavernarakis N, Kroemer G. Morselli E, et al. Cell Death Dis. 2010;1(1):e10. doi: 10.1038/cddis.2009.8. Cell Death Dis. 2010. PMID: 21364612 Free PMC article.
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