Real-time, in vivo monitoring and pharmacokinetics of valproic acid via a novel biomarker in exhaled breath - PubMed (original) (raw)
. 2011 May 7;47(17):4884-6.
doi: 10.1039/c1cc10343a. Epub 2011 Mar 4.
Affiliations
- PMID: 21373707
- DOI: 10.1039/c1cc10343a
Real-time, in vivo monitoring and pharmacokinetics of valproic acid via a novel biomarker in exhaled breath
Gerardo Gamez et al. Chem Commun (Camb). 2011.
Abstract
Extractive electrospray ionization mass spectrometry is shown to allow real-time, in vivo drug monitoring and pharmacokinetic measurement in a non-invasive, pain-free manner as demonstrated by the mass spectral measurement of a novel exhaled breath biomarker for valproic acid, a medication used to control epilepsy.
© The Royal Society of Chemistry 2011
Similar articles
- Development of extractive electrospray ionization ion trap mass spectrometry for in vivo breath analysis.
Ding J, Yang S, Liang D, Chen H, Wu Z, Zhang L, Ren Y. Ding J, et al. Analyst. 2009 Oct;134(10):2040-50. doi: 10.1039/b821497b. Epub 2009 Jul 24. Analyst. 2009. PMID: 19768211 - Real-time monitoring of exhaled drugs by mass spectrometry.
Berchtold C, Bosilkovska M, Daali Y, Walder B, Zenobi R. Berchtold C, et al. Mass Spectrom Rev. 2014 Sep-Oct;33(5):394-413. doi: 10.1002/mas.21393. Epub 2013 Nov 22. Mass Spectrom Rev. 2014. PMID: 24272872 Review. - Identification of 2-alkenals, 4-hydroxy-2-alkenals, and 4-hydroxy-2,6-alkadienals in exhaled breath condensate by UHPLC-HRMS and in breath by real-time HRMS.
García-Gómez D, Martínez-Lozano Sinues P, Barrios-Collado C, Vidal-de-Miguel G, Gaugg M, Zenobi R. García-Gómez D, et al. Anal Chem. 2015 Mar 3;87(5):3087-93. doi: 10.1021/ac504796p. Epub 2015 Feb 13. Anal Chem. 2015. PMID: 25646646 - Human exhaled air analytics: biomarkers of diseases.
Buszewski B, Kesy M, Ligor T, Amann A. Buszewski B, et al. Biomed Chromatogr. 2007 Jun;21(6):553-66. doi: 10.1002/bmc.835. Biomed Chromatogr. 2007. PMID: 17431933 Review.
Cited by
- In Vivo Low-Temperature Plasma Ionization Mass Spectrometry (LTP-MS) Reveals Regulation of 6-Pentyl-2H-Pyran-2-One (6-PP) as a Physiological Variable during Plant-Fungal Interaction.
Torres-Ortega R, Guillén-Alonso H, Alcalde-Vázquez R, Ramírez-Chávez E, Molina-Torres J, Winkler R. Torres-Ortega R, et al. Metabolites. 2022 Dec 8;12(12):1231. doi: 10.3390/metabo12121231. Metabolites. 2022. PMID: 36557269 Free PMC article. - Personalised therapeutic management of epileptic patients guided by pathway-driven breath metabolomics.
Singh KD, Osswald M, Ziesenitz VC, Awchi M, Usemann J, Imbach LL, Kohler M, García-Gómez D, van den Anker J, Frey U, Datta AN, Sinues P. Singh KD, et al. Commun Med (Lond). 2021 Aug 2;1:21. doi: 10.1038/s43856-021-00021-3. eCollection 2021. Commun Med (Lond). 2021. PMID: 35602217 Free PMC article. - Pharmacokinetics of intravenous and inhaled salbutamol and tobramycin: An exploratory study to investigate the potential of exhaled breath condensate as a matrix for pharmacokinetic analysis.
Kruizinga MD, Birkhoff WAJ, van Esdonk MJ, Klarenbeek NB, Cholewinski T, Nelemans T, Dröge MJ, Cohen AF, Zuiker RGJA. Kruizinga MD, et al. Br J Clin Pharmacol. 2020 Jan;86(1):175-181. doi: 10.1111/bcp.14156. Epub 2020 Jan 3. Br J Clin Pharmacol. 2020. PMID: 31658494 Free PMC article. - Determination of valproic acid and 3-heptanone in plasma using air-assisted liquid-liquid microextraction with the assistance of vortex: Application in the real samples.
Feriduni B, Barzegar M, Sadeghvand S, Shiva S, Khoubnasabjafari M, Jouyban A. Feriduni B, et al. Bioimpacts. 2019;9(2):105-113. doi: 10.15171/bi.2019.14. Epub 2019 Mar 8. Bioimpacts. 2019. PMID: 31334042 Free PMC article. - Reactive Laser Ablation Electrospray Ionization Time-Resolved Mass Spectrometry of Click Reactions.
van Geenen FAMG, Franssen MCR, Zuilhof H, Nielen MWF. van Geenen FAMG, et al. Anal Chem. 2018 Sep 4;90(17):10409-10416. doi: 10.1021/acs.analchem.8b02290. Epub 2018 Aug 13. Anal Chem. 2018. PMID: 30063331 Free PMC article.
MeSH terms
Substances
LinkOut - more resources
Full Text Sources