Flaxseed dietary fibers suppress postprandial lipemia and appetite sensation in young men - PubMed (original) (raw)
Randomized Controlled Trial
doi: 10.1016/j.numecd.2011.03.004. Epub 2011 Jul 29.
Affiliations
- PMID: 21802266
- DOI: 10.1016/j.numecd.2011.03.004
Randomized Controlled Trial
Flaxseed dietary fibers suppress postprandial lipemia and appetite sensation in young men
M Kristensen et al. Nutr Metab Cardiovasc Dis. 2013 Feb.
Abstract
Background and aim: Dietary fibers (DF) are linked to a reduced risk of life-style diseases, which relate to their physiological effects in the gastrointestinal tract. The aim was to examine whether flaxseed DF-enriched meals suppress postprandial lipemia and reduce appetite.
Methods and results: Four different iso-caloric meals were tested in 18 young men in a double-blind randomized crossover design. Test meals were served after an overnight fast. DF content and source were: control (C): 1.4 g/MJ; whole flaxseed (WF): 2.4 g/MJ from whole flaxseeds; low-mucilage dose (LM): 2.4 g/MJ from flaxseed DF; high-mucilage dose (HM): 3.4 g/MJ from flaxseed DF. During the 7 h test day, subjective appetite sensation was assessed using visual analogue scales and appetite-regulating hormones, and lipemia and glycemia were measured, after which ad libitum energy intake was recorded. There was a significant time × meal effect on triacylglycerols (TG) (p = 0.02) and an 18% smaller area under the curve (AUC) for TG after meal HM compared to meal C was observed (p < 0.01). AUC for insulin was smaller after both LM and HM meals compared to C and WF meals. Higher mean ratings of satiety (p < 0.01) and fullness (p = 0.03) was seen following the HM meal compared to meal C. AUC for ghrelin, CCK and GLP-1 and ad libitum energy intake did not differ between meals, but ghrelin response exhibited a different response pattern after the mucilage-containing meals.
Conclusion: These findings suggest that flaxseed DF may suppress postprandial lipemia and appetite although subsequent energy intake was not affected.
Copyright © 2011 Elsevier B.V. All rights reserved.
Similar articles
- Semisolid meal enriched in oat bran decreases plasma glucose and insulin levels, but does not change gastrointestinal peptide responses or short-term appetite in healthy subjects.
Juvonen KR, Salmenkallio-Marttila M, Lyly M, Liukkonen KH, Lähteenmäki L, Laaksonen DE, Uusitupa MI, Herzig KH, Poutanen KS, Karhunen LJ. Juvonen KR, et al. Nutr Metab Cardiovasc Dis. 2011 Sep;21(9):748-56. doi: 10.1016/j.numecd.2010.02.002. Epub 2010 Jun 4. Nutr Metab Cardiovasc Dis. 2011. PMID: 20605427 Clinical Trial. - Independent and combined effects of eating rate and energy density on energy intake, appetite, and gut hormones.
Karl JP, Young AJ, Rood JC, Montain SJ. Karl JP, et al. Obesity (Silver Spring). 2013 Mar;21(3):E244-52. doi: 10.1002/oby.20075. Obesity (Silver Spring). 2013. PMID: 23592679 Clinical Trial. - Appetite hormones and energy intake in obese men after consumption of fructose, glucose and whey protein beverages.
Bowen J, Noakes M, Clifton PM. Bowen J, et al. Int J Obes (Lond). 2007 Nov;31(11):1696-703. doi: 10.1038/sj.ijo.0803665. Epub 2007 Jun 26. Int J Obes (Lond). 2007. PMID: 17593904 Clinical Trial. - Effect of Polydextrose on Subjective Feelings of Appetite during the Satiation and Satiety Periods: A Systematic Review and Meta-Analysis.
Ibarra A, Astbury NM, Olli K, Alhoniemi E, Tiihonen K. Ibarra A, et al. Nutrients. 2016 Jan 14;8(1):45. doi: 10.3390/nu8010045. Nutrients. 2016. PMID: 26784221 Free PMC article. Review. - Systematic review and meta-analysis of the effect of meal intake on postprandial appetite-related gastrointestinal hormones in obese children.
Nguo K, Walker KZ, Bonham MP, Huggins CE. Nguo K, et al. Int J Obes (Lond). 2016 Apr;40(4):555-63. doi: 10.1038/ijo.2015.256. Epub 2015 Dec 21. Int J Obes (Lond). 2016. PMID: 26686004 Review.
Cited by
- Glycaemic and Appetite Suppression Effect of a Vegetable-Enriched Bread.
Amoah I, Cairncross C, Merien F, Rush E. Amoah I, et al. Nutrients. 2021 Nov 27;13(12):4277. doi: 10.3390/nu13124277. Nutrients. 2021. PMID: 34959829 Free PMC article. Clinical Trial. - The effects of flaxseed supplementation on metabolic status in women with polycystic ovary syndrome: a randomized open-labeled controlled clinical trial.
Haidari F, Banaei-Jahromi N, Zakerkish M, Ahmadi K. Haidari F, et al. Nutr J. 2020 Jan 24;19(1):8. doi: 10.1186/s12937-020-0524-5. Nutr J. 2020. PMID: 31980022 Free PMC article. Clinical Trial. - Effects of resistant starch on glycemic response, postprandial lipemia and appetite in subjects with type 2 diabetes.
García-Vázquez C, Ble-Castillo JL, Arias-Córdova Y, Ramos-García M, Olvera-Hernández V, Guzmán-Priego CG, Martínez-López MC, Jiménez-Domínguez G, Hernández-Becerra JA. García-Vázquez C, et al. Eur J Nutr. 2023 Aug;62(5):2269-2278. doi: 10.1007/s00394-023-03154-4. Epub 2023 Apr 21. Eur J Nutr. 2023. PMID: 37083722 Clinical Trial. - Flaxseed Mucilage (IQP-LU-104) Reduces Body Weight in Overweight and Moderately Obese Individuals in a 12-week, Three-Arm, Double-Blind, Randomized, and Placebo-Controlled Clinical Study.
Bongartz U, Hochmann U, Grube B, Uebelhack R, Alt F, Erlenbeck C, Peng LV, Chong PW, De Costa P. Bongartz U, et al. Obes Facts. 2022;15(3):395-404. doi: 10.1159/000522082. Epub 2022 Feb 7. Obes Facts. 2022. PMID: 35130547 Free PMC article. Clinical Trial. - Comparative Effects of Native and Defatted Flaxseeds on Intestinal Enzyme Activity and Lipid Metabolism in Rats Fed a High-Fat Diet Containing Cholic Acid.
Opyd PM, Jurgoński A, Juśkiewicz J, Fotschki B, Koza J. Opyd PM, et al. Nutrients. 2018 Aug 28;10(9):1181. doi: 10.3390/nu10091181. Nutrients. 2018. PMID: 30154372 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources
Medical
Miscellaneous