Expression of the yeast DNA primase gene, PRI1, is regulated within the mitotic cell cycle and in meiosis - PubMed (original) (raw)
Expression of the yeast DNA primase gene, PRI1, is regulated within the mitotic cell cycle and in meiosis
L H Johnston et al. Mol Gen Genet. 1990 Mar.
Abstract
Mitotic cultures synchronised either by a feed-starve protocol or by elutriation have been used to show that the Saccharomyces cerevisiae DNA primase I gene is periodically expressed in the cell cycle. The transcript increases many-fold in late G1 and reaches a peak at the same time as four other genes essential for DNA synthesis, CDC8, CDC9, CDC21 and POL1. The primase I transcript is also regulated in meiosis, reaching maximal levels during premeiotic DNA synthesis.
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