Idiopathic ventricular fibrillation - PubMed (original) (raw)
Review
Idiopathic ventricular fibrillation
S Viskin et al. Am Heart J. 1990 Sep.
Abstract
A review of the literature dealing with sudden death revealed 19 articles in which ostensibly healthy patients with documented VF unrelated to any known cardiac or noncardiac etiology are reported. Fifty-four patients fulfilling the criteria for idiopathic VF, including 14 patients investigated at our institution, are described. The mean age of patients for studies that reported age data was 36 years, with a male-to-female ratio of 2.5 to 1. Over 90% of the patients required resuscitation, while syncope due to nonsustained VF occurred in the rest. Diagnosis of VF was preceded by syncope in one fourth of the patients. Holter monitoring and exercise stress tests were often unrewarding. Available electrophysiologic data revealed a 69% inducibility rate of sustained ventricular tachyarrhythmias using nonaggressive protocols of ventricular stimulation in most cases. Induced tachyarrhythmias were poorly tolerated, and were mostly of polymorphic configuration. Class IA antiarrhythmic agents were highly effective in preventing reinduction of these arrhythmias. Available figures suggest an 11% rate of sudden death within 1 year of diagnosis. Appropriate antiarrhythmic therapy appears to improve prognosis. Reviewed data suggest that idiopathic VF represents an underestimated cause of sudden cardiac death in ostensibly healthy patients. An international registry of patients with idiopathic VF is warranted.
Similar articles
- Idiopathic ventricular fibrillation: clinical, electrophysiologic characteristics and long-term outcomes.
Tsai CF, Chen SA, Tai CT, Chiang CE, Ding YA, Chang MS. Tsai CF, et al. Int J Cardiol. 1998 Mar 13;64(1):47-55. doi: 10.1016/s0167-5273(98)00004-7. Int J Cardiol. 1998. PMID: 9579816 - Late outcome of survivors of idiopathic ventricular fibrillation.
Mewis C, Kühlkamp V, Spyridopoulos I, Bosch RF, Seipel L. Mewis C, et al. Am J Cardiol. 1998 Apr 15;81(8):999-1003. doi: 10.1016/s0002-9149(98)00079-4. Am J Cardiol. 1998. PMID: 9576160 - Idiopathic ventricular tachycardia and fibrillation.
Belhassen B, Viskin S. Belhassen B, et al. J Cardiovasc Electrophysiol. 1993 Jun;4(3):356-68. doi: 10.1111/j.1540-8167.1993.tb01236.x. J Cardiovasc Electrophysiol. 1993. PMID: 8269305 Review. - Role of programmed ventricular stimulation in patients with idiopathic dilated cardiomyopathy and documented sustained ventricular tachyarrhythmias: inducibility and prognostic value in 102 patients.
Chen X, Shenasa M, Borggrefe M, Block M, Hindricks G, Martinez-Rubio A, Haverkamp W, Willems S, Böcker D, Mäkijärvi M, et al. Chen X, et al. Eur Heart J. 1994 Jan;15(1):76-82. doi: 10.1093/oxfordjournals.eurheartj.a060383. Eur Heart J. 1994. PMID: 8174587 - Sudden arrhythmic cardiac death--mechanisms, resuscitation and classification: the Seattle perspective.
Greene HL. Greene HL. Am J Cardiol. 1990 Jan 16;65(4):4B-12B. doi: 10.1016/0002-9149(90)91285-e. Am J Cardiol. 1990. PMID: 2404396 Review.
Cited by
- Contributions of Israel to the field of clinical cardiac electrophysiology and implantable devices.
Belhassen B. Belhassen B. Heart Rhythm O2. 2024 Feb 21;5(2):67-84. doi: 10.1016/j.hroo.2023.11.006. eCollection 2024 Feb. Heart Rhythm O2. 2024. PMID: 38545322 Free PMC article. No abstract available. - Short-coupled Purkinje ectopy inducible by pharmacological and hyperventilation tests.
Grifoni G, Haissaguerre M, Bongiorni MG, Benali K, Soldati E, Zucchelli G. Grifoni G, et al. HeartRhythm Case Rep. 2023 Oct 31;10(1):68-71. doi: 10.1016/j.hrcr.2023.10.025. eCollection 2024 Jan. HeartRhythm Case Rep. 2023. PMID: 38264118 Free PMC article. No abstract available. - Outcomes in Dutch DPP6 risk haplotype for familial idiopathic ventricular fibrillation: a focused update.
Bergeman AT, Hoeksema WF, van der Ree MH, Boersma LVA, Yap SC, Verheul LM, Hassink RJ, van der Crabben SN, Volders PGA, van der Werf C, Wilde AAM, Postema PG; European Reference Network for rare, low prevalence and complex diseases of the heart: ERN GUARD-Heart. Bergeman AT, et al. Neth Heart J. 2023 Aug;31(7-8):309-314. doi: 10.1007/s12471-023-01792-1. Epub 2023 Jul 27. Neth Heart J. 2023. PMID: 37498467 Free PMC article. - Inducibility of Short-Coupled Purkinje Ectopy by Pharmacological Tests in Patients With Spontaneous Short-Coupled Idiopathic Ventricular Fibrillation.
Haissaguerre M, Duchateau J, Laredo M, Lavergne T, Winum PF, Cheniti G, Waintraub X, Samson S, Surget E, Tixier R, Sacher F, Marijon E, Bernus O, Gandjbakhch E. Haissaguerre M, et al. Circulation. 2023 Jul 4;148(1):70-72. doi: 10.1161/CIRCULATIONAHA.122.063578. Epub 2023 Jul 3. Circulation. 2023. PMID: 37399260 Free PMC article. No abstract available. - Sex-related differences in incidence, phenotype and risk of sudden cardiac death in inherited arrhythmia syndromes.
Asatryan B, Barth AS. Asatryan B, et al. Front Cardiovasc Med. 2023 Jan 4;9:1010748. doi: 10.3389/fcvm.2022.1010748. eCollection 2022. Front Cardiovasc Med. 2023. PMID: 36684594 Free PMC article. Review.