PRDM16 (1p36) translocations define a distinct entity of myeloid malignancies with poor prognosis but may also occur in lymphoid malignancies - PubMed (original) (raw)

• Acute myeloid leukemia with rare recurring translocations-an overview of the entities included in the international consensus classification.
  Rørvik SD, Torkildsen S, Bruserud Ø, Tvedt THA. Rørvik SD, et al. Ann Hematol. 2024 Apr;103(4):1103-1119. doi: 10.1007/s00277-024-05680-5. Epub 2024 Mar 6. Ann Hematol. 2024. PMID: 38443661 Free PMC article. Review.
• A distinct human cell type expressing MHCII and RORγt with dual characteristics of dendritic cells and type 3 innate lymphoid cells.
  Ulezko Antonova A, Lonardi S, Monti M, Missale F, Fan C, Coates ML, Bugatti M, Jaeger N, Fernandes Rodrigues P, Brioschi S, Trsan T, Fachi JL, Nguyen KM, Nunley RM, Moratto D, Zini S, Kong L, Deguine J, Peeples ME, Xavier RJ, Clatworthy MR, Wang T, Cella M, Vermi W, Colonna M. Ulezko Antonova A, et al. Proc Natl Acad Sci U S A. 2023 Dec 26;120(52):e2318710120. doi: 10.1073/pnas.2318710120. Epub 2023 Dec 18. Proc Natl Acad Sci U S A. 2023. PMID: 38109523 Free PMC article.
• 3q26.2/MECOM Rearrangements by Pericentric Inv(3): Diagnostic Challenges and Clinicopathologic Features.
  Tang Z, Wang W, Yang S, El Achi H, Fang H, Nahmod KA, Toruner GA, Xu J, Thakral B, Ayoub E, Issa GC, Yin CC, You MJ, Miranda RN, Khoury JD, Medeiros LJ, Tang G. Tang Z, et al. Cancers (Basel). 2023 Jan 11;15(2):458. doi: 10.3390/cancers15020458. Cancers (Basel). 2023. PMID: 36672407 Free PMC article.
• Recurrent Translocations in Topoisomerase Inhibitor-Related Leukemia Are Determined by the Features of DNA Breaks Rather Than by the Proximity of the Translocating Genes.
  Lomov NA, Viushkov VS, Ulianov SV, Gavrilov AA, Alexeyevsky DA, Artemov AV, Razin SV, Rubtsov MA. Lomov NA, et al. Int J Mol Sci. 2022 Aug 29;23(17):9824. doi: 10.3390/ijms23179824. Int J Mol Sci. 2022. PMID: 36077220 Free PMC article.
• International Consensus Classification of Myeloid Neoplasms and Acute Leukemias: integrating morphologic, clinical, and genomic data.
  Arber DA, Orazi A, Hasserjian RP, Borowitz MJ, Calvo KR, Kvasnicka HM, Wang SA, Bagg A, Barbui T, Branford S, Bueso-Ramos CE, Cortes JE, Dal Cin P, DiNardo CD, Dombret H, Duncavage EJ, Ebert BL, Estey EH, Facchetti F, Foucar K, Gangat N, Gianelli U, Godley LA, Gökbuget N, Gotlib J, Hellström-Lindberg E, Hobbs GS, Hoffman R, Jabbour EJ, Kiladjian JJ, Larson RA, Le Beau MM, Loh ML, Löwenberg B, Macintyre E, Malcovati L, Mullighan CG, Niemeyer C, Odenike OM, Ogawa S, Orfao A, Papaemmanuil E, Passamonti F, Porkka K, Pui CH, Radich JP, Reiter A, Rozman M, Rudelius M, Savona MR, Schiffer CA, Schmitt-Graeff A, Shimamura A, Sierra J, Stock WA, Stone RM, Tallman MS, Thiele J, Tien HF, Tzankov A, Vannucchi AM, Vyas P, Wei AH, Weinberg OK, Wierzbowska A, Cazzola M, Döhner H, Tefferi A. Arber DA, et al. Blood. 2022 Sep 15;140(11):1200-1228. doi: 10.1182/blood.2022015850. Blood. 2022. PMID: 35767897 Free PMC article.