Vanillin catabolism in Rhodococcus jostii RHA1 - PubMed (original) (raw)

Vanillin catabolism in Rhodococcus jostii RHA1

Hao-Ping Chen et al. Appl Environ Microbiol. 2012 Jan.

Abstract

Genes encoding vanillin dehydrogenase (vdh) and vanillate O-demethylase (vanAB) were identified in Rhodococcus jostii RHA1 using gene disruption and enzyme activities. During growth on vanillin or vanillate, vanA was highly upregulated while vdh was not. This study contributes to our understanding of lignin degradation by RHA1 and other actinomycetes.

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Figures

Fig 1

Fig 1

(A) Vanillin catabolic pathway in RHA1. (B) Vanillate _O_-demethylase gene cluster. The vanA and vanB genes encode the oxygenase and reductase components, respectively, of vanillate _O_-demethylase. Gene ro04162 is predicted to encode an IclR family transcriptional regulator. Acetyl-CoA, acetyl coenzyme A.

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